Results 51 to 60 of about 2,688,243 (319)

Murine Nephrotoxic Nephritis as a Model of Chronic Kidney Disease

International Journal of Nephrology, 2018
Using the nonaccelerated murine nephrotoxic nephritis (NTN) as a model of chronic kidney disease (CKD) could provide an easily inducible model that enables a rapid test of treatments.
M. K. E. Ougaard, P. H. Kvist, H. E. Jensen, C. Hess, I. Rune, H. Søndergaard   +5 more
doaj   +1 more source

A mathematical model for the burden of diabetes and its complications

, 2004
Background The incidence and prevalence of diabetes are increasing all over the world. Complications of diabetes constitute a burden for the individuals and the whole society.
K Achouayb, Achouayb, K, Boutayeb A, Chetouani, A, Achouayb K, EH Twizell, Twizell EH, Twizell, E H, Boutayeb, A, A Boutayeb, Chetouani A, A Chetouani   +11 more
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Serum PSA levels fluctuations in patients with non–muscle-invasive bladder cancer (NMIBC) undergoing BCG therapy: a prospective study

BMC Urology
Background Intravesical bacillus Calmette–Guérin (BCG) therapy is the standard adjuvant treatment for intermediate-high risk non–muscle-invasive bladder cancer (NMIBC).
Seyyed Parham Ahmadi, Fatemeh Sadabadi, Bahareh Khoshbin, Zhila Sheikhi   +3 more
doaj   +1 more source

Profiling oxidative stress markers and cardiovascular complications in chronic kidney disease patients supplemented with vitamin E

Archives of Medical Science: Atherosclerotic Diseases
Introduction Cardiovascular diseases are common complications in chronic kidney disease (CKD). Oxidative stress associated with renal and metabolic dysfunctions is one of the cardiovascular complications (CVC) in haemodialysis patients.
Leila Azouaou, Mounir Adnane, Omar Chabati, Medina Arab, Toualbi Chahine, Henni Chader   +5 more
doaj   +1 more source

Increased mitochondrial proton leak and glycolysis in peripheral blood mononuclear cells in type-1-diabetes

Heliyon, 2022
Changes in cellular bioenergetics such as mitochondrial respiration and glycolysis may play a role in the pathogenesis of various diseases including type 1 diabetes (T1D).
Joana Mendes Lopes de Melo, Jens Christian Laursen, Niels Søndergaard-Heinrich, Ida Kirstine Bull Rasmussen, Christian Stevns Hansen, Marie Frimodt-Møller, Peter Rossing, Joachim Størling   +7 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Advanced Glycation End Products and Inflammation in Type 1 Diabetes Development

Cells, 2022
Type 1 diabetes (T1D) is an autoimmune disease in which the β-cells of the pancreas are attacked by the host’s immune system, ultimately resulting in hyperglycemia. It is a complex multifactorial disease postulated to result from a combination of genetic
Chenping Du, Rani O. Whiddett, Irina Buckle, Chen Chen, Josephine M. Forbes, Amelia K. Fotheringham   +5 more
doaj   +1 more source

Cardiovascular complications in patients with PHEO: A mini-review

, 2010
Phaeochromocytomas are rare neuroendocrine tumours secreting high levels of catecholamines, able to exert serious metabolic and cardiovascular effects. The serious and potentially lethal cardiovascular complications of these tumours are due to the potent
GALETTA, FABIO, BERNINI, GIAMPAOLO, CINI G, POUPAK F, CARPI A, ANTONELLI, ALESSANDRO, CARDIOVASCULAR COMPLICATIONS IN PATIENTS WITH PHEO A. MINI REVIEW, FRANZONI, FERDINANDO, SANTORO, GINO, TOCCHINI L   +9 more
core   +1 more source

Maternal obesity and labour complications following induction of labour in prolonged pregnancy [PDF]

, 2011
Objective: To investigate the effect of maternal obesity on mode of delivery following induction of labour (IOL) for prolonged pregnancy and subsequent intrapartum and neonatal complications. Design: Retrospective (historical) cohort study.
S Quenby, S Arrowsmith, Wray, Susan, Quenby, Siobhan, Arrowsmith, Sarah, S Wray   +5 more
core   +1 more source