Results 51 to 60 of about 3,074,721 (303)

Impact of comply-or-explain approach in new regulatory policy on Japanese mutual fund markets

open access: yesHeliyon
The Japan Financial Services Agency (JFSA) has expressed concerns within the mutual fund industry regarding high fees, low performance, and distributors' marketing practices that encourage investors to frequently trade funds.
Tomoki Kitamura, Kozo Omori
doaj   +1 more source

Reasonably good corporate governance [PDF]

open access: yes, 2014
Attempts to determine what constitutes “good” corporate governance have become mired in the quicksand of the ethical conflict between duty and utility, virtue and rights, as well as the fight over for whose good the organization exists.
Nordberg, Donald
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

An Exploration of Beliefs about Gender Differences in Language Use

open access: yesJournal of Language and Education, 2018
It is the natural order of things for humans to acquire beliefs and conform to stereotypes in an attempt to explain phenomena surrounding them. These mental constructs are known to have a pervasive influence on the way people think and act, and therefore
Esma Latić, Amna Brdarević Čeljo
doaj   +1 more source

The Measurement of Quality of Semantic Standards: the Application of a Quality Model on the SETU standard for eGovernment [PDF]

open access: yes, 2011
eGovernment interoperability should be dealt with using high-quality standards. A quality model for standards is presented based on knowledge from the software engineering domain. In the tradition of action research the model is used on the SETU standard,
Bekkum, Michael van   +3 more
core   +2 more sources

Barriers to Implementing the International Integrated Reporting Framework: A Contemporary Academic Perspective [PDF]

open access: yes, 2017
Purpose: This paper is motivated by the International Integrated Reporting Council’s (IIRC) call for feedback from all stakeholders with knowledge of the International Integrated Reporting Framework , and specifically of the enablers, incentives and ...
ASX Corporate Governance Council (ASX CGC)   +11 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Farmers' land‐use decision‐making: A dynamical modelling approach that integrates qualitative knowledge about social norms into a quantitative model

open access: yesPeople and Nature, 2023
The concept of the homo oeconomicus is often used to model human behaviour in economic contexts. However, other factors like tradition or the preference to comply with social norms can play a role in decision‐making processes.
Irina Vortkamp, Frank M. Hilker
doaj   +1 more source

Retailer compliance with energy label regulations [PDF]

open access: yes, 2013
With the Framework Directive 92/75/EEC on Energy Labelling of Household Appliances, the European Union introduced a labelling system that applies to major household appliances.
Faure, Corinne   +2 more
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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