Results 1 to 10 of about 15,584 (218)

Bisimulation for component-based development

Journal of Computer Science and Technology, 2002
Guaranteeing that assembled components will behave as required is one of the main aspects in working with Component-Based Development. In this paper we present a formal approach for tackling this problem by applying the concept of bisimulation ...
Elsa Clara Estévez, Pablo Rubén Fillottrani   +1 more
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Paeoniflorin and Hydroxysafflor Yellow A in Xuebijing Injection Attenuate Sepsis-Induced Cardiac Dysfunction and Inhibit Proinflammatory Cytokine Production

Frontiers in Pharmacology, 2021
Sepsis-induced myocardial dysfunction is a major contributor to the poor outcomes of septic shock. As an add-on with conventional sepsis management for over 15 years, the effect of Xuebijing injection (XBJ) on the sepsis-induced myocardial dysfunction ...
Xin-Tong Wang, Xin-Tong Wang, Zhen Peng, Zhen Peng, Ying-Ying An, Ying-Ying An, Ting Shang, Ting Shang, Guangxu Xiao, Guangxu Xiao, Shuang He, Shuang He, Xi Chen, Han Zhang, Yuefei Wang, Tao Wang, Jun-Hua Zhang, Xiumei Gao, Yan Zhu, Yan Zhu, Yuxin Feng, Yuxin Feng   +21 more
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Xuebijing injection inhibited neutrophil extracellular traps to reverse lung injury in sepsis mice via reducing Gasdermin D

Frontiers in Pharmacology, 2022
The mortality of sepsis and septic shock remains high worldwide. Neutrophil extracellular traps (NETs) release is a major cause of organ failure and mortality in sepsis.
Ting Shang, Ting Shang, Zhi-Sen Zhang, Zhi-Sen Zhang, Xin-Tong Wang, Xin-Tong Wang, Jing Chang, Jing Chang, Meng-En Zhou, Meng-En Zhou, Ming Lyu, Ming Lyu, Shuang He, Shuang He, Jian Yang, Jian Yang, Yan-Xu Chang, Yuefei Wang, Ming-Chun Li, Xiumei Gao, Yan Zhu, Yan Zhu, Yuxin Feng, Yuxin Feng   +23 more
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Galectin-3 Mediated Inflammatory Response Contributes to Neurological Recovery by QiShenYiQi in Subacute Stroke Model

Frontiers in Pharmacology, 2021
Effective therapies for stroke are still limited due to its complex pathological manifestations. QiShenYiQi (QSYQ), a component-based Chinese medicine capable of reducing organ injury caused by ischemia/reperfusion, may offer an alternative option for ...
Yule Wang, Yule Wang, Yule Wang, Shuang He, Shuang He, Xinyan Liu, Xinyan Liu, Zhixiong Li, Zhixiong Li, Lin Zhu, Lin Zhu, Guangxu Xiao, Guangxu Xiao, Xiaoli Du, Xiaoli Du, Xiaoli Du, Hongxia Du, Hongxia Du, Wen Zhang, Wen Zhang, Yiqian Zhang, John Orgah, John Orgah, Yuxin Feng, Yuxin Feng, Boli Zhang, Yan Zhu, Yan Zhu   +27 more
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Protecting Intestinal Microenvironment Alleviates Acute Graft-Versus-Host Disease

Frontiers in Physiology, 2021
Acute gut graft-versus-host disease (aGVHD) is a leading threat to the survival of allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients. Abnormal gut microbiota is correlated with poor prognosis in allo-HSCT recipients.
Zhengcan Zhou, Zhengcan Zhou, Ting Shang, Ting Shang, Xiurong Li, Hongyan Zhu, Hongyan Zhu, Yu-Bo Qi, Xin Zhao, Xi Chen, Zhe-Xin Shi, Guixiang Pan, Guixiang Pan, Yue-Fei Wang, Yue-Fei Wang, Guanwei Fan, Xiumei Gao, Yan Zhu, Yan Zhu, Yuxin Feng, Yuxin Feng   +20 more
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ACT001 improved cardiovascular function in septic mice by inhibiting the production of proinflammatory cytokines and the expression of JAK-STAT signaling pathway

Frontiers in Pharmacology, 2023
Sepsis is a life-threatening multiple organ dysfunction syndrome (MODS) caused by a microbial infection that leads to high morbidity and mortality worldwide. Sepsis-induced cardiomyopathy (SIC) and coagulopathy promote the progression of adverse outcomes
Zhen Peng, Zhen Peng, Xiaolong Lv, Xiaolong Lv, Xintong Wang, Xintong Wang, Ting Shang, Ting Shang, Jing Chang, Jing Chang, Khalid Salahdiin, Khalid Salahdiin, Yue Guo, Yue Guo, Zhisen Zhang, Zhisen Zhang, Ru Shen, Ru Shen, Ming Lyu, Ming Lyu, Shuang He, Shuang He, Jian Yang, Jian Yang, Yuefei Wang, Xiumei Gao, Yan Zhu, Yan Zhu, Yuxin Feng, Yuxin Feng   +29 more
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Authentication of Zingiber Species Based on Analysis of Metabolite Profiles

Frontiers in Plant Science, 2021
Zingiber corallinum and Zingiber montanum, which belong to the Zingiberaceae family, are traditional Chinese folk medicinal herbs in Guizhou and Yunnan Province of China.
Chenxi Wang, Yue Zhang, Hui Ding, Meifang Song, Jiaxin Yin, Heshui Yu, Zheng Li, Lifeng Han, Zhonglian Zhang   +8 more
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Traditional Herbal Medicine Discovery for the Treatment and Prevention of Pulmonary Arterial Hypertension

Frontiers in Pharmacology, 2021
Pulmonary arterial hypertension (PAH) is characterized by pulmonary artery remodeling that may subsequently culminate in right heart failure and premature death.
Zhifeng Xue, Zhifeng Xue, Yixuan Li, Yixuan Li, Mengen Zhou, Mengen Zhou, Zhidong Liu, Zhidong Liu, Guanwei Fan, Guanwei Fan, Xiaoying Wang, Xiaoying Wang, Yan Zhu, Yan Zhu, Jian Yang, Jian Yang   +15 more
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SUMO1 regulates post-infarct cardiac repair based on cellular heterogeneity

Journal of Pharmaceutical Analysis, 2023
Small ubiquitin-related modifier (SUMOylation) is a dynamic post-translational modification that maintains cardiac function and can protect against a hypertrophic response to cardiac pressure overload.
Zhihao Liu, Xiaozhi Liu, Li Liu, Ying Wang, Jie Zheng, Lan Li, Sheng Li, Han Zhang, Jingyu Ni, Chuanrui Ma, Xiumei Gao, Xiyun Bian, Guanwei Fan   +12 more
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Integration of UHPLC/Q-OrbitrapMS-based metabolomics and activities evaluation to rapidly explore the anti-inflammatory components from lasianthus

Heliyon, 2023
Lasianthus, belonging to Rubiaceae, has been verified to improve clinical syndrome in immune diseases (e.g., hepatitis, nephritis, and rheumatoid arthritis).
Lele Zhang, Shaofei Song, Biying Chen, Rongrong Li, Liming Wang, Chenxi Wang, Lifeng Han, Zhifei Fu, Zhonglian Zhang, Qilong Wang, Heshui Yu   +10 more
doaj   +1 more source