Results 111 to 120 of about 1,365,388 (312)
Фабрика онтолого-керованих інформаційно-пошукових систем [PDF]
, 2014 У роботі запропоновано використання методології компонентно-орієнтованої програмної інженерії при розробці онтолого-керованих інформаційно-пошукових систем.
Глибовець, Микола +1 more
core
Molecular Oncology, EarlyView.Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho +11 more
wiley +1 more source
A Component-Oriented Programming for Embedded Mobile Robot Software
International Journal of Advanced Robotic Systems, 2008 Applying software reuse to many Embedded Real-Time (ERT) systems poses significant challenges to industrial software processes due to the resource-constrained and real-time requirements of the systems.
Safaai Deris +2 more
doaj
Subgraph Query for Building Service-Based Systems
IEEE Access, 2019 Given the broad applications of service-oriented architecture (SOA) in service-oriented software engineering, service-based systems (SBSs) built from existing Web services are becoming increasingly popular.
Jintao Wu +5 more
doaj +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Advanced 3D-CAD Design Methods in Education and Research [PDF]
Journal of Systemics, Cybernetics and Informatics, 2009 The integration of advanced virtual engineering methods into 3D-CAD based development processes leads to increased requirements, concerning the software packages as well as regarding the applied procedures and strategies.
Mario Hirz +2 more
doaj
Incremental Learning from Multi-level Monitoring Data and Its Application to Component Based Software Engineering [PDF]
, 2017 Salman Taherizadeh, Vlado Stankovski
openalex +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
RAGE Architecture for Reusable Serious Gaming Technology Components
International Journal of Computer Games Technology, 2016 For seizing the potential of serious games, the RAGE project—funded by the Horizon-2020 Programme of the European Commission—will make available an interoperable set of advanced technology components (software assets) that support game studios at serious
Wim van der Vegt +4 more
doaj +1 more source