Results 131 to 140 of about 1,365,388 (312)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Microelectromechanical Systems (MEMS) Resistive Heaters as Circuit Protection Devices [PDF]

, 2013
With increased opportunities for the exploitation (i.e., reverse engineering) of vulnerable electronic components and systems, circuit protection has become a critical issue.
Coutu, Ronald A., Jr., Ostrow, Scott A.
core   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Research and application of key technologies for data delivery in railway engineering design based on metadata

High-Speed Railway
In view of the problems of inconsistent data semantics, inconsistent data formats, and difficult data quality assurance between the railway engineering design phase and the construction and operation phase, as well as the difficulty in fully realizing ...
Xiangru Lyu, Xunxiao Yin, Kun Wang, Yongwen Wei   +3 more
doaj   +1 more source

Constructing component-based software engineering environments: issues and experiences [PDF]

, 2000
John Grundy, W.B. Mugridge, John Hosking
openalex   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

The Experimental Study of the Validity of the Lagrange–Helmholtz Relationship in Geomagnetic Fields

Sensors
Streak cameras, known for their ultra-high spatiotemporal resolution, rely heavily on the spatial resolution capabilities of their core component, the streak tube, to ensure engineering stability.
Jing-jin Zhang, Yu-wei Xu, Zeng-zhou Yi, Qin-lao Yang, Jun-kun Huang, Fang-ke Zong   +5 more
doaj   +1 more source

Analysis and Estimation of Interaction and Reusability Complexities of Components in Component-Based Software Engineering

, 2020
Nidhi Mehra, Divya Kapil
openalex   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Grid Computing and Component-Based Software Engineering in Computer Supported Collaborative Learning [PDF]

, 2004
Miguel L. Bote‐Lorenzo, Juan I. Asensio‐Pérez, Guillermo Vega‐Gorgojo, Luis M. Vaquero, Eduardo Gómez‐Sánchez, Yannis Dimitriadis   +5 more
openalex   +1 more source