Results 61 to 70 of about 307,163 (278)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Component-Based Java Legacy Code Refactoring
Revista Facultad de Ingeniería Universidad de Antioquia, 2013 Component-Based Software Engineering (CBSE) claims to improve software modularisation and to embed architectural concerns. Refactoring Java legacy code with CBSE in mind requires first assessing the compliance of legacy code with component programming ...
Hugo Arboleda +2 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Software reuse in industrial robotics: A systematic mapping
Revista Iberoamericana de Automática e Informática Industrial RIAI, 2020 There is a tendency to use software reuse approaches in the domain of industrial robotic systems, to accelerate their development. Although some studies show the benefits of developing using different reuse approaches, these practices have not been ...
A. Solis, J. Hurtado
doaj +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Integration of Simulink Models with Component-based Software Models
Advances in Electrical and Computer Engineering, 2008 Model based development aims to facilitate the development of embedded control systems by emphasizing the separation of the design level from the implementation level.
MARIAN, N., TOP, S.
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
A component-based method for developing web applications
Revista Colombiana de Computación, 2003 We describe, in this paper, a component-based software engineering method for helping development teams to plan, organize, control, and develop web applications.
Jonas A. Montilva C., Judith Barrios A.
doaj
Ranking and selection of commercial off-the-shelf using fuzzy distance based approach [PDF]
Decision Science Letters, 2015 There is a tremendous growth of the use of the component based software engineering (CBSE) approach for the development of software systems. The selection of the best suited COTS components which fulfils the necessary requirement for the development of ...
Rakesh Garg, R. K. Sharma, Kapil Sharma
doaj +1 more source