Results 81 to 90 of about 1,365,388 (312)

Ranking and selection of commercial off-the-shelf using fuzzy distance based approach [PDF]

Decision Science Letters, 2015
There is a tremendous growth of the use of the component based software engineering (CBSE) approach for the development of software systems. The selection of the best suited COTS components which fulfils the necessary requirement for the development of ...
Rakesh Garg, R. K. Sharma, Kapil Sharma
doaj   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A component-based method for developing web applications

Revista Colombiana de Computación, 2003
We describe, in this paper, a component-based software engineering method for helping development teams to plan, organize, control, and develop web applications.
Jonas A. Montilva C., Judith Barrios A.
doaj  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Algebraic specifications and refinement for component-based development using RAISE

Journal of Computer Science and Technology, 2002
There are two main activities in Component-Based Development: component development, where we build libraries for general use, and component integration, where we assemble an application from existing components.
Elsa Clara Estévez, Pablo Rubén Fillottrani   +1 more
doaj  

Semantic web services for simulation component reuse and interoperability: An ontology approach [PDF]

, 2010
Commercial-off-the-shelf (COTS) Simulation Packages (CSPs) are widely used in industry primarily due to economic factors associated with developing proprietary software platforms.
Bell, D, de Cesare, S, Fishwick, PA, Lycett, M, Mustafee, N, Taylor, SJE   +5 more
core  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Development of Vacuum Vessel Design and Analysis Module for CFETR Integration Design Platform

Science and Technology of Nuclear Installations, 2016
An integration design platform is under development for the design of the China Fusion Engineering Test Reactor (CFETR). It mainly includes the integration physical design platform and the integration engineering design platform.
Chen Zhu, Minyou Ye, Xufeng Liu, Shenji Wang, Shifeng Mao, Zhongwei Wang, Yi Yu   +6 more
doaj   +1 more source

Integrating Cyber-Physical Systems in a Component-Based Approach for Smart Homes

Sensors, 2018
Integration of different cyber-physical systems involves a development process that takes into account some solutions for intercommunicating and interoperating heterogeneous devices.
Javier Criado, José Andrés Asensio, Nicolás Padilla, Luis Iribarne   +3 more
doaj   +1 more source