Results 31 to 40 of about 5,508,214 (319)

Dual drug-loaded nano-platform for targeted cancer therapy: toward clinical therapeutic efficacy of multifunctionality

open access: yesJournal of Nanobiotechnology, 2020
Background Poor targeting and penetration of chemotherapy drugs in solid tumors, and the development of resistance to chemotherapeutic agents are currently hindering the therapy of breast cancer; meanwhile, breast cancer metastasis is one of the leading ...
Zhe Ma   +7 more
doaj   +1 more source

Species diversity analysis of commercial Mantidis Ootheca samples contaminated by store pests based on DNA metabarcoding

open access: yesBMC Genomics, 2022
Mantidis Ootheca (Sangpiaoxiao, mantis egg case) is a typical multi-origin Chinese medicinal material. The Chinese Pharmacopoeia stipulates that the Mantidis Ootheca originates from three species of Mantis: Tenodera sinensis, Statilia maculate, and ...
Liuwei Xu   +7 more
doaj   +1 more source

A Component Model Engineered with Components and Aspects [PDF]

open access: yes, 2006
This paper presents AOKell, a framework for engineering component-based systems. This framework implements the Fractal model, a hierarchical and dynamic component model. The novelty of this paper lies in the presentation of AOKell, an implementation of the Fractal model with aspects. Two dimensions can be isolated with Fractal: the functional dimension,
Seinturier, Lionel   +3 more
openaire   +2 more sources

Linking component importance to optimisation of preventive maintenance policy [PDF]

open access: yes, 2016
In reliability engineering, time on performing preventive maintenance (PM) on a component in a system may affect system availability if system operation needs stopping for PM.
Chen, Yi   +3 more
core   +1 more source

Component-by-component construction of good intermediate-rank lattice rules

open access: yes, 2003
It is known that the generating vector of a rank-1 lattice rule can be constructed component-by-component to achieve strong tractability error bounds in both weighted Korobov spaces and weighted Sobolev spaces.
Joe, Stephen, Kuo, Frances Y.
core   +1 more source

Ex vivo piperaquine resistance developed rapidly in Plasmodium falciparum isolates in northern Cambodia compared to Thailand

open access: yesMalaria Journal, 2016
Background The recent dramatic decline in dihydroartemisinin-piperaquine (DHA-PPQ) efficacy in northwestern Cambodia has raised concerns about the rapid spread of piperaquine resistance just as DHA-PPQ is being introduced as first-line therapy in ...
Suwanna Chaorattanakawee   +21 more
doaj   +1 more source

A Component-by-Component Construction for the Trigonometric Degree [PDF]

open access: yes, 2012
We propose an alternative to the algorithm from Cools, Kuo, Nuyens (Computing 87(1–2):63–89, 2010), for constructing lattice rules with good trigonometric degree. The original algorithm has construction cost \(O(\vert {\mathcal{A}}_{d}(m)\vert + dN\log N)\) for an N-point lattice rule in d dimensions having trigonometric degree m, where the set ...
Achtsis, Nico, Nuyens, Dirk
openaire   +1 more source

Combination of cell-penetrating peptides with nanomaterials for the potential therapeutics of central nervous system disorders: a review

open access: yesJournal of Nanobiotechnology, 2021
Although nanomedicine have greatly developed and human life span has been extended, we have witnessed the soared incidence of central nervous system (CNS) diseases including neurodegenerative diseases (Alzheimer’s disease, Parkinson’s disease), ischemic ...
Ying Zhang   +5 more
doaj   +1 more source

Experimental study on vibration and noise characteristics of small fan motors

open access: yesNihon Kikai Gakkai ronbunshu, 2014
In this paper, the phenomenon of vibration and noise in a small fan motor caused by electromagnetic forces were experimentally investigated. First, vibration characteristics of the fan motor in a non-operating state were determined by experimental modal ...
Masaki OGUSHI   +6 more
doaj   +1 more source

Tumor microenvironment: a prospective target of natural alkaloids for cancer treatment

open access: yesCancer Cell International, 2021
Malignant tumor has become one of the major diseases that seriously endangers human health. Numerous studies have demonstrated that tumor microenvironment (TME) is closely associated with patient prognosis.
Yanming Luo   +8 more
doaj   +1 more source

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