Results 81 to 90 of about 948,302 (303)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Motives of practice in the field of non-competitive physical activity [PDF]

open access: yes, 2011
Resumen basado en el de la publicaciónSe analizan cuáles son los motivos de práctica en el ámbito de la actividad física no competitiva. Para ello se administró la escala de medición de los motivos de actividad física revisada (MPAM-R, Motives for ...
Abraldes Valeiras, J. Arturo   +3 more
core   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Creating a typology of tobacco farms according to determinants of diversification in Valle de Lerma (Salta-Argentina) [PDF]

open access: yes, 2010
The objective of this article is to identify typical tobacco farms according to determinants of diversification that can be used to explore possibilities of diversification in the province of Salta (Northwest of Argentina).
Berentsen, P.B.M.   +2 more
core   +4 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Pequeñas unidades de ceba de Cebú comercial en pastoreo con baja suplementación.

open access: yesRevista de Producción Animal, 2017
El objetivo del trabajo fue describir y agrupar unidades de ceba de toros Cebú comerciales en pastoreo con baja suplementación. Se estudiaron 44 unidades de producción de carne bovina pertenecientes a cooperativas de crédito y servicio integradas por ...
Guillermo E. Guevara Viera   +6 more
doaj  

La administración española de Puerto Rico: las cuentas públicas a finales de su colonización [PDF]

open access: yes, 2012
Los sucesivos gobiernos españoles se vieron obligados a reajustar en diversas ocasiones sus políticas de gasto público en la colonia de Puerto Rico durante su último siglo de dominación.
Escobar Pérez, Bernabé   +2 more
core  

Estadística avanzada en medicina: el análisis de componentes principales

open access: yesRevista del Hospital Italiano de Buenos Aires, 2011
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openaire   +2 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

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