Results 111 to 120 of about 314,040 (284)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
ALEA III, Composers' Workshop, April 27, 1991 [PDF]
, 1991 This is the concert program of ALEA III, Composers' Workshop performance on Saturday, April 27, 1991 at 7:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
PIANO MUSIC BY GALINA USTVOLSKAYA, OR LADY WITH A HAMMER [PDF]
Studiul Artelor şi Culturologie: Istorie, Teorie, Practică, 2019 The article is a survey of piano creation by Galina Ivanovna Ustvolskaya, one of the most mysterious figures in Russian music of the twentieth century.
STEPANOVA IRINA, SIMONEANŢ ELENA
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Live Coding: A New Approach to Musical Composition
Dancecult: Journal of Electronic Dance Music Culture, 2018 Alexandra Cárdenas
doaj +1 more source
THE INTERPRETATIVE ACTIVITY OF THE COMPOSER GHEORGHE NEAGA [PDF]
Studiul Artelor şi Culturologie: Istorie, Teorie, Practică, 2015 Gheorghe Neagas name is highlighted among the representatives of the local music school and among the creators who ensures the continuity and ancestry of some genuine achievements. His artistic figure can be considered a specific and therewith a complex
CHICIUC NATALIA
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
COMPOSITION PORTRAIT IRINA ODĂGESCU-ȚUȚUIANU [PDF]
Studiul Artelor şi Culturologie: Istorie, Teorie, Practică, 2019 In May 2017 the composer Irina Odăgescu-Țuțuianu reached the beautiful age of 80 years! Representative of a modernism of a moderated persuasion, within the meaning of making a synthesis between the old and the new, balance between the symphonic ...
RADU-ŢAGA CONSUELA
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