Results 131 to 140 of about 386,145 (366)
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Boston University Wind Ensemble, October 8, 2009 [PDF]
This is the concert program of the Boston University Wind Ensemble performance on Thursday, October 8, 2009 at 7:30 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
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Floris Schuiling, The Instant Composers Pool and Improvisation Beyond Jazz [PDF]
Clément Canonne
openalex +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Live Coding: A New Approach to Musical Composition
Alexandra Cárdenas
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
“IN MEMORIAM” DAN VOICULESCU. “CODA” TO “A BOOK WITHOUT END”
The composer, musicologist and Professor Dan Voiculescu, pivotal figure of the Transylvanian musical landscape, recently left this life. He leaves for posterity a valuable artistic and scientific legacy.
Bianca Ţiplea TEMEŞ
doaj
Supporting creative composition: the FrameWorks approach
We present a new system for music composition using structured sequences. FrameWorks has been developed on the basis of Task Analysis research studying composition processes and other user-centred design techniques.
Polfreman, Richard
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