Results 211 to 220 of about 386,145 (366)

The Composer as Intellectual

, 2023
Ana R. Alonso-Minutti
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Advances in Data-Driven Early Warning Systems for Sepsis Recognition and Intervention in Emergency Care: A Systematic Review of Diagnostic Performance and Clinical Outcomes. [PDF]

Cureus
Al-Juhani A, Desoky R, Iskander Z, Alshehri KT, Alshehri AA, Almuhaimid A, Alharbi NL, Mominah RH, Al-Humoud FM, Desoky A.   +9 more
europepmc   +1 more source

Composer and Theorist Joel Mandelbaum on Microtonality

, 2018
Juhani Nuorvala
openalex   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Did Orpheus have stage fright? To oneself, to the other, to the transcendent: steps for coping with music performance anxiety. [PDF]

Front Psychol
Šimunovič N.
europepmc   +1 more source

Soviet Composers and the Development of Soviet Music. By Stanley D. Krebs. New York: W. W. Norton, 1970. 364 pp. $11.50. [PDF]

, 1971
Malcolm Brown
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Pharmacokinetic characterization and exposure-response relationship of crovalimab in the COMMODORE 1, 2 and 3 and COMPOSER trials of patients with paroxysmal nocturnal haemoglobinuria. [PDF]

Br J Clin Pharmacol
Cosson V, Fu R, Kulasekararaj A, Nishimura JI, Panse J, Röth A, Scheinberg P, Tong H, Yoon SS, Beveridge L, Gotanda K, Jaminion F, Henrich A, Lundberg P, Shi D, Sreckovic S, Zhang Y, Zhang Z, Benkali K, Buatois S.   +19 more
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source