Results 181 to 190 of about 1,624,361 (249)

Experimental investigation of mechanical properties of sustainable silica sand reinforced AA6061 composites subjected to thermomechanical treatment. [PDF]

Sci Rep
Sadanand RV, Nayak SY, Prabhu A.
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Fabrication and evaluation of PLA/CPP/GO composite scaffolds: the role of graphene oxide content in regulating properties. [PDF]

RSC Adv
Liu S, Zhang C, Li J, Zhang J, Wang Y, Hua J, Zheng Y.   +6 more
europepmc   +1 more source

Extrudability and Mechanical Properties of Wood–Sodium Silicate Composites with Hemp Fiber Reinforcement for Additive Manufacturing [PDF]

Nagendra G. Tanikella, Alexandra M. Lehman-Chong, Armando G. McDonald, Michael R. Maughan   +3 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Tunable Fly Ash-Based Geopolymer Fibers for Multivariate Heavy-Metal Adsorption: Optimization and Mechanistic Insights. [PDF]

Materials (Basel)
Luo G, Zhou Y, Liao S, Onutai S.
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Analysis of thermal and dynamic mechanical properties of epoxy bio-composites reinforced with sisal fibers and carbon nanotubes. [PDF]

Sci Rep
Rao DK, Kaithwas CK, Jain N, Shivaramakrishna U, Thimmaiah J, Goudar DM, Pinto DG, Bhat SK, Raju K.   +8 more
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Study on pistachio shell filled PLA composites for FDM-based processing. [PDF]

Sci Rep
Begum SR, Devan BA, Kavya S, Pranav H, Rakul R, Vasumathi M, Senthamaraikannan P, Adediran AA, Saravana Kumar M.   +8 more
europepmc   +1 more source