Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi +5 more
wiley +1 more source
Physical Properties of Ovalbumin/Sodium Carboxymethyl Cellulose Composite Gels Induced by Glucono-δ-Lactone and Heat Treatment. [PDF]
Zhang X, Li L, Wang L, Xu W.
europepmc +1 more source
Most autophagic cell death studies lack evidence of causality
Of 104 studies claiming autophagic cell death (ACD), only 13 demonstrated both causality and exclusion of apoptosis to confirm true ACD. Most studies relied on correlation‐level data or measured autophagy in isolation, revealing pervasive methodological shortcomings.
Ali Burak Özkaya, Yasmin Ghaseminejad
wiley +1 more source
Biomimetic KcsA channels enabled by 1D MOF-in-2D COF. [PDF]
Sun Q +8 more
europepmc +1 more source
In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki +3 more
wiley +1 more source
Practical Algal Control in Lower Yangtze Reservoirs Using Composite Microfiltration Physical Enclosure. [PDF]
Xu B +5 more
europepmc +1 more source
Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma +10 more
wiley +1 more source
An injectable bioceramics-containing composite hydrogel promoting innervation for pulp-dentin complex repair. [PDF]
Tao X +6 more
europepmc +1 more source
Key role for inhibins in effective T cell activation, migration and Th17 differentiation
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco +5 more
wiley +1 more source
Development of hybrid fiber-reinforced vinyl ester composites for civil and automotive applications. [PDF]
Vignesh V +6 more
europepmc +1 more source

