Results 221 to 230 of about 1,673,967 (249)

Engineering of a kaolin/SLS-functionalized biochar@β-cyclodextrin composite for adsorption of <i>o</i>-nitrophenol; optimization, mechanistic study, and Box-Behnken design. [PDF]

RSC Adv
Eltaweil AS, Al Harby N, El Batouti M, Abd El-Monaem EM.   +3 more
europepmc   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Relation Between Adiposity Measures and the Risk of a Composite of Cardiovascular Events, Diabetes, and Cancer in Patients With Cardiovascular Disease. [PDF]

Clin Obes
Bhattacharya R, Visseren FLJ, van der Meer MG, Teraa M, Dorresteijn JAN, Ruigrok YM, van Sloten TT, UCC‐Smart Study Group.   +7 more
europepmc   +1 more source

Determination of Mechanical Performance of Epoxy Composites with magnesium oxide (MgO) Addition

Zaynab Miftah Alsaweeb, Salma Al-Tohami Al-Ahwal   +1 more
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Facile Fabrication of Attapulgite-Modified Chitosan Composite Aerogels with Enhanced Mechanical Strength and Flame Retardancy for Thermal Insulation. [PDF]

Polymers (Basel)
Cheng S, Shao Y, Chen M, Wang C, Zhu X, Zhang X, Fu B.   +6 more
europepmc   +1 more source

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Clinical evaluation of restorations made of ELS extra low shrinkage versus APT advanced polymer technology resin composite: a prospective randomized controlled clinical trial up to 3 years. [PDF]

BMC Oral Health
Özsoy-Kaner A, Kuşdemir M, Öztürk-Bozkurt F, Toz-Akalin T, Özcan M.   +4 more
europepmc   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Investigation of Phenolic Vinyl Resin/Graphite Composite Bipolar Plates for Proton Exchange Membrane Fuel Cells. [PDF]

ACS Omega
Zhang K, Li L, Liu C, Ye K.
europepmc   +1 more source