Results 101 to 110 of about 2,175,387 (287)
Robust Compositional Data Analysis
, 2011 Many practical data sets contain outliers or other forms of data inhomogeneities. Robust statistics offers concepts how to deal with these situations where the data do not follow strict model assumptions. These concepts are designed for the usual Euclidean space, and they can be easily applied to compositional data if they are ...
Filzmoser, Peter +2 more
openaire +3 more sources
CODSTRAN: Composite durability structural analysis [PDF]
CODSTRAN (COmposite Durability STRuctural ANalysis) is an integrated computer program being developed for the prediction of defect growth and fracture of composite structures subjected to service loads and environments. CODSTRAN is briefly described with
Chamis, C. C., Smith, G. T.
core +1 more source
Boron aluminum composite structures [PDF]
, 1972 Design, analysis and fabrication techniques have been developed for boron-aluminum composite structure technology and were compared with those of conventional metal structure technology to evaluate relative ...
Jackson, R. E.
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Compositional Performance Analysis
, 2017 In this chapter we review the foundations Compositional Performance Analysis (CPA) and explain many extensions which support its application in design practice. CPA is widely used in automotive system design where it successfully complements or even replaces simulation based approaches.
Hofman, Robin +2 more
openaire +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Probabilistic composite analysis [PDF]
Formal procedures are described which are used to computationally simulate the probabilistic behavior of composite structures. The computational simulation starts with the uncertainties associated with all aspects of a composite structure (constituents ...
Chamis, C. C., Murthy, P. L. N.
core +1 more source
Synthesis and characterization of hydroxyapatite-gelatine composite materials for orthopaedic application [PDF]
, 2016 The composite materials based on hydroxyapatite (HA) and gelatine (Gel) with addition of silver and zirconium oxide were obtained. The study investigates a combination of low powered ultrasonic irradiation and low concentration of gelatine in the co ...
Bolshanina, S. +7 more
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source