Results 131 to 140 of about 2,199,917 (306)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Microfracture in high temperature metal matrix laminates [PDF]

Computational simulation procedures are described to evaluate the composite microfracture behavior, establish the hierarchy/sequence of fracture modes, and the influence of compliant layers and partial debonding on composite properties and microfracture ...
Chamis, Christos C., Gotsis, Pascal K., Mital, Subodh K.   +2 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

High-performance photoelectrochemical cells with MoS2 nanoflakes/TiO2 photoanode on 3D porous carbon spun fabric

Advanced Sensor and Energy Materials
A solar-driven photoelectrochemical (PEC) cell is emerging as one of the promising clean hydrogen generation systems. Engineering of semiconductor heterojunctions and surface morphologies of photoelectrodes in a PEC cell has been a primitive approach to ...
Hyunjin Cho, Ji-Yeon Kim, Dong Su Shin, Joo Song Lee, Jaeho Shim, In-Ho Lee, Won Kook Choi, Namhee Kwon, Soohyung Park, Mehmet Suha Yazici, Young Jae Park, Ju Hee You, Seok-Ho Seo, Donghee Park, Dong Ick Son   +14 more
doaj   +1 more source

Computational simulation of intermingled-fiber hybrid composite behavior [PDF]

Three-dimensional finite-element analysis and a micromechanics based computer code ICAN (Integrated Composite Analyzer) are used to predict the composite properties and microstresses of a unidirectional graphite/epoxy primary composite with varying ...
Chamis, Christos C., Mital, Subodh K.
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Development of methologies to study the damage tolerance of aeronautical and aerospace composite structures [PDF]

, 2008
Mechanics of Advanced Materials research group (Department of Continuum Mechanics and Structural Analysis) of the University Carlos III of Madrid (Spain) offers their experience in the analysis and modelization of high and low velocity impact behaviour ...
Barbero Pozuelo, Enrique, Sánchez Sáez, Sonia   +1 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Composite Analysis of the Virome and Bacteriome of HIV/HPV Co-Infected Women Reveals Proxies for Immunodeficiency. [PDF]

Viruses, 2019
Siqueira JD, Curty G, Xutao D, Hofer CB, Machado ES, Seuánez HN, Soares MA, Delwart E, Soares EA.   +8 more
europepmc   +1 more source