Results 121 to 130 of about 140,782 (296)

Property Evaluation of AA2014 Reinforced with Synthesized Novel Mixture Processed through Squeeze Casting Technique

Journal of Manufacturing and Materials Processing
Aluminum alloy–graphene metal matrix composite is largely used for structural applications in the aerospace and space exploration sector. In this work, the preprocessed powder particles (AA 2014 and graphene) were used as a reinforcement material in a ...
Venkatraman Manokaran, Anthony Xavior Michael   +1 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Fabrication of glass/madar fibers reinforced hybrid epoxy composite: a comprehensive study on the material stability

Scientific Reports
The present study aims to examine the characteristics of a composite material composed of glass/madar fibers and porcelain particles, which are reinforced with epoxy. A compression molding technique achieves the fabrication of this composite.
Thandavamoorthy Raja, D. Yuvarajan, Saheb Ali, G. Dhanraj, Nandagopal Kaliappan   +4 more
doaj   +1 more source

Study and Preparation of ceramic and composite materials with luminescent properties

, 2011
Study and Preparation of ceramic and composite materials with luminescent properties. Following the results obtained with mixture L1 sintered at 1650°C, in the period November 2012-February 2011, new mixtures have been prepared and ...
Piancastelli Andreana, Serantoni Marina, Esposito Laura, Melandri Cesare   +3 more
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Transformation composition – property dependencies of binary homogeneous mixtures

Тонкие химические технологии, 2013
The possible transformations of composition – property dependencies of binary homogeneous mixtures are considered. Transformations of the first multiplicity leading to the emergence of internal singular points are followed by changes in the types of points: the topological minimum becomes topological maximum (and vice versa).
L. A. Serafimov, V. M. Raeva
openaire   +1 more source

Gold nanoparticles–polyaniline composite material: Synthesis, structure and electrical properties

, 2011
Gold nanoparticles-polyaniline composite materials were synthesised and their structure and electrical properties were analised. Different stabilizing agents were used resulting in the formation of nanoparticles with sizes within 5-10 nm.
Tatiana Berzina, Pucci Andrea, Victor Erokhin, Fontana Marco P, Erokhin Victor, Giacomo Ruggeri, Berzina Tatiana, Andrea Pucci, Marco P. Fontana, Ruggeri Giacomo   +9 more
core   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Law of Mixture for Macroscopic Properties of Composite Materials.

Journal of Society of Materials Engineering for Resources of Japan, 1991
SEKINE, Hideki, TANNO, Ken, KONDO, Toshimi, OZAWA, Yoshihito   +3 more
openaire   +2 more sources