Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Development and Performance Evaluation of Composite Modified Nano-TiO<sub>2</sub> for Permeable Asphalt Mixtures: Focus on Exhaust Degradation and Dispersion Properties. [PDF]
Materials (Basel)Li Y +5 more
europepmc +1 more source
COMPOSITE ADHESIVE MIXTURES BASED ON CEMENT: PROPERTIES, APPLICATIONS, AND ADVANCEMENTS
Composite adhesive mixtures based on cement have gained widespread use in construction and other industrial applications due to their superior bonding properties, durability, and versatility. This thesis aims to explore the formulation, mechanical properties, and potential applications of cement-based adhesive mixtures.
Mustafaqulov, Javohir +1 more
openaire +1 more source
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Eco-friendly starch-nanocellulose bio-nanocomposite films with improved structure-property interactions. [PDF]
Nanoscale AdvReza MS +5 more
europepmc +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Fabrication and Electrocatalytic Activity of Fe-Cu/C Composites Based on Copper Ferrite Modified with Graphene Oxide and Graphitic Carbon Nitride. [PDF]
Materials (Basel)Vissurkhanova YA +3 more
europepmc +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Ionic Liquid-Assisted Acetylated Xylan Coatings Reinforced with CuO and ZnO Nanoparticles for Food Packaging Papers. [PDF]
Polymers (Basel)Nechita P, Năstac SM.
europepmc +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source