Results 91 to 100 of about 143,009 (292)

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Dimensional instability of cement bonded particleboard: Modelling CBPB as a composite of two materials [PDF]

open access: yes, 2004
Copyright @ Springer Verlag. This is a post print version of the article. The official published version can be obtained from the link below.Previous papers have quantitatively indicated that the total movement of cement bonded particleboard (CBPB) is ...
Dinwoodie, JM   +3 more
core   +1 more source

Impact of Mixture Ratio on Bio-Composite Material from Bamboo and Recycled Polyethylene Terephthalate (PET)

open access: yesABUAD Journal of Engineering Research and Development
The study investigated the impact of mixture ratio on various physico-chemical and mechanical properties of a bio-composite material made from bamboo and recycled polyethylene terephthalate (PET).
Abiodun Ayodeji Ojetoye   +5 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

A New Heavy Tailed Class of Distributions Which Includes the Pareto

open access: yesRisks, 2019
In this paper, a new heavy-tailed distribution, the mixture Pareto-loggamma distribution, derived through an exponential transformation of the generalized Lindley distribution is introduced.
Deepesh Bhati   +2 more
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

open access: yesFEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini   +3 more
wiley   +1 more source

Study effect of active flux on mechanical properties of TIG welding process

open access: yesResults in Engineering
The mechanical properties of low carbon steel welded using TIG process are studied in relation with the active fluxes, silicon oxide (SiO₂), manganese oxide (MnO₂), and the composite of 50 % SiO₂ and 50 % MnO₂. The research aims to investigate the impact
Zainab Hussein Mohsein   +2 more
doaj   +1 more source

Research on the Influence of Nanocarbon/Copolymer SBS/Rubber Powder Composite Modification on the Properties of Asphalt and Mixtures

open access: yesAdvances in Materials Science and Engineering, 2020
To expand the application range of modified asphalt and mixtures and effectively reduce the aggregation of nanomaterials in asphalt, nanocarbon/styrene butadiene styrene (SBS)/rubber powder composite-modified asphalt is proposed.
Wenhui Zhao   +5 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

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