Results 61 to 70 of about 1,356 (213)

Analysis of the spectrum of antimicrobial activity of the composite mixture of Macadamia ternifolia nut oil and Opuntia ficus indica L. cactus seeds and its application in medical practice [PDF]

BIO Web of Conferences
The paper considers the results of the analysis of the spectrum of antimicrobial activity of the composite mixture of Macadamia ternifolia nut oil and Opuntia ficus indica L. cactus seed oil.
Lyashchuk Yulia, Ovchinnikov Alexey, Samarin Gennady, Ruzin Semyon, Novak Alexandra, Sankin Anton   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Microstructure and Mechanical Behavior of CaCO3-Doped Al–Al2O3 Composite Foams Produced by Powder Metallurgy

Journal of Advanced Research in Natural and Applied Sciences
In this study, closed-cell composite metal foam production was performed using the powder metallurgy method. Therefore, 7, 12, and 17 wt.% CaCO3 as a foaming agent was added to the Al–Al2O3 powder mixture containing 5 wt.% Al2O3 after the grinding ...
Nebi Demirbağ, Serkan Abalı
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Analysis of effective thermal conductivity for mineral cast material structures with varying epoxy content using TPS method

Materials Research, 2013
Conventionally, cast iron is the material used for high speed machine tool structures. As an alternate material to improve the structural properties, composite materials are being used, which are known to exhibit excellent thermal and mechanical ...
A. Selvakumar, P. V. Mohanram
doaj  

Microstructure and Mechanical Properties of Diamond–Ceramic Composites Fabricated via Reactive Spark Plasma Sintering

Ceramics
In order to prepare diamond composites with excellent mechanical properties under non-extreme conditions, in this study, a diamond–ceramic composite was successfully prepared via reactive spark plasma sintering using a diamond–Ti–Si powder mixture as the
Yunwei Shi, Lanxin Hu, Aiyang Wang, Chun Liu, Qianglong He, Weimin Wang   +5 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Impact of Mixture Ratio on Bio-Composite Material from Bamboo and Recycled Polyethylene Terephthalate (PET)

ABUAD Journal of Engineering Research and Development
The study investigated the impact of mixture ratio on various physico-chemical and mechanical properties of a bio-composite material made from bamboo and recycled polyethylene terephthalate (PET).
Abiodun Ayodeji Ojetoye, Olutosin Olufisayo Ilori, Shalom Chitom Iwedi, Kelechi Valentine Obiechefu, Precious Arinze Okezue, Kareem Feranmi   +5 more
doaj   +1 more source