Results 41 to 50 of about 1,180,463 (291)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Interaction curves for vibration and buckling of thin-walled composite box beams under axial loads and end moments [PDF]

, 2010
Interaction curves for vibration and buckling of thin-walled composite box beams with arbitrary lay-ups under constant axial loads and equal end moments are presented.
Lee, Jaehong, Vo, Thuc
core   +1 more source

An Assessment of the Behaviour of Ceiling Beams of Different Structure

Applied Sciences
The article focuses on floor composite beams used in buildings. Within the scope of the conducted analytical and numerical studies, the authors compared the typical solution—namely, the T-shaped reinforced concrete beam—with various types of composite ...
Katarzyna Ciesielczyk, Robert Studziński, Marcin Chybiński, Jacek Ścigałło, Wojciech Szymkuć, Jakub Krzysztof Grabski, Tomasz Marciniak, Łukasz Polus   +7 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Geometrical nonlinear analysis of thin-walled composite beams using finite element method based on first order shear deformation theory [PDF]

, 2011
Based on a seven-degree-of-freedom shear deformable beam model, a geometrical nonlinear analysis of thin-walled composite beams with arbitrary lay-ups under various types of loads is presented.
Lee, Jaehong, Vo, Thuc
core   +1 more source

Structural performance of composite beams: effects of continuity and slenderness ratio

Journal of Engineering and Applied Science
An experimental study was conducted to investigate the performance of both simply supported and continuous steel beams acting compositely with reinforced concrete slabs using profiled steel sheeting and shear connectors.
Ahmed Safy, Mahmoud Lasheen, Amr Shaat, Nahla Hassan   +3 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Flexural–torsional coupled vibration and buckling of thin-walled open section composite beams using shear-deformable beam theory [PDF]

, 2009
A general analytical model based on shear-deformable beam theory has been developed to study the flexural–torsional coupled vibration and buckling of thin-walled open section composite beams with arbitrary lay-ups.
Lee, Jaehong, Vo, Thuc
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Vibration and buckling of cross-ply composite beams using refined shear deformation theory [PDF]

, 2012
Vibration and buckling analysis of cross-ply composite beams using refined shear deformation theory is presented. The theory accounts for the parabolical variation of shear strains through the depth of beam.
Inam, Fawad, Vo, Thuc
core