Results 31 to 40 of about 2,341 (249)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

An Analysis of a Persian Archery manuscript written by Kapur Čand

open access: yesRevista de Artes Marciales Asiáticas, 2013
The present article deals with an analysis of an undated Persian archery manuscript titled Resāle-ye Kamāndāri [Archery Manuscript] written by Kapur Čand. It is written in Persian and judging by the style it should have been written by a Persian. Persian
Bede Dwyer   +1 more
doaj  

Original Composite Bow of the “Manchu” Tradition from the Collections of the Museum of Siberian Archaeology and Ethnography named after V. M. Florinsky of TSU (Tomsk).

open access: yesВестник Новосибирского государственного университета. Серия: история, филология
Purpose. The Museum of Siberian Archaeology and Ethnography at Tomsk State University named after V. M. Florinsky (Tomsk) houses a unique item belonging to the “family of Central Asian” composite bows, which has no analogues among known items in terms of
R. M. Kharitonov, I. N. Korobeinikov
doaj   +1 more source

Comprehensive study of the early Yakut Sergelyakh burial of the XV — beginning of the XVI centuries

open access: yesВестник археологии, антропологии и этнографии, 2016
The paper presents a comprehensive study of graves which relate to rare burial sites of the early stage of ethnic history of the Yakuts. The burial belongs to an equestrian warrior.
Bravina R.I.   +11 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Development of a Morphing Landing Gear Composite Door for High Speed Compound Rotorcraft

open access: yesAerospace, 2020
In the framework of fast rotorcraft, smoothness and flushness of external aerodynamic surfaces present challenges for high-speed conditions, where aerodynamics is the driver of helicopter performance.
Antonio Chiariello   +5 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Comparison of the adhesion performances of traditional and new generation adhesives used in the making of Turkish bows

open access: yesTurkish Journal of Forestry
From primitive societies to today's modern armies, mankind has engaged in competition and warfare since its existence, developing various weapon systems for prevailing in these conflicts.
Oktay Gönültaş, Salih Parlak
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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