Results 201 to 210 of about 105,618 (248)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

The mediating role of emotional intelligence in the relationship between physical education and sports teachers' mindfulness and psychological resilience. [PDF]

Front Psychol
Dursun M, Kan E, Can HC, Yarayan YE, Tozoğlu E, Şebin K, Buzdağlı Y.   +6 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Mechanism and control strategies for asymmetric floor heave in extra-thick coal seam roadways under high stress. [PDF]

Sci Rep
Zhang J, Sun J, Wang B, Yang T, He Y, Gao S, Qin G, Zhang Y.   +7 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Liposome-based drug delivery systems for skin wound healing: a promising drug delivery strategy. [PDF]

Front Bioeng Biotechnol
Ma Z, Zhang K, Luo J, Chen S, Tan S, Ma D.   +5 more
europepmc   +1 more source

Geometry-Driven Structural Efficiency and Normative Performance of Miriti-Based Sandwich Composite Roofing Tiles. [PDF]

Polymers (Basel)
Silva ACSD, Ribeiro MM, Silva DS, Junio RFP, Monteiro SN, Rodrigues JDS.   +5 more
europepmc   +1 more source

Layered grouting reinforcement technology for coal-rock composite roof: A treatment system based on model experiments. [PDF]

Sci Rep
Liao Z, Li P, Zhao X, Wu G, Zhao L.
europepmc   +1 more source

Illusory ownership of one's younger face facilitates access to childhood episodic autobiographical memories. [PDF]

Sci Rep
Gupta U, Bright P, Clarke A, Zafar W, Recarte-Perez P, Aspell JE.   +5 more
europepmc   +1 more source