Results 91 to 100 of about 129,604 (261)

Measuring Equitable Prosperity in the EU-27: Introducing the IDDO, a Composite Index of Growth and Income Inequality (2005–2024)

open access: yesWorld
This article introduces the Index of Distributive and Developmental Outlook (IDDO), a composite indicator designed to jointly assess economic performance and income inequality across EU-27 Member States.
Narcis Eduard Mitu, George Teodor Mitu
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

The LESG Index for Assessing Structural Coherence in National Development Systems

open access: yesApplied Sciences
This study introduces the LESG index, a composite analytical framework designed to assess the structural coherence of national development systems by integrating logistics capability, governance quality, and sustainability performance.
Panagiotis Karountzos   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Geoprocessamento e a promoção da saúde: desigualdades sociais e ambientais em São Paulo

open access: yesRevista de Saúde Pública
OBJETIVO: Caracterizar as desigualdades sociais, que se configuram em condições de risco aos agravos respiratórios em crianças e descrever os usos de técnicas de geoprocessamento na identificação de grupos sociais homogêneos e as ações de intervenção no ...
Anna Maria Chiesa   +2 more
doaj  

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Building a Composite Index for Measuring the Sustainability of Egyptian Cities: A Case Study of Delta Cities بناء مؤشر مركب لقياس استدامة المدن المصرية – دراسة حالة مدن الدلتا

open access: yesJournal of Urban Research
unplanned urban expansion, and climate changes that threaten natural resources and infrastructure. In this context, building a comprehensive and clear tool to measure sustainability is a necessary step to support decision-makers in achieving urban ...
Yasmine Ahmed Samak   +2 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

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