Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Fatigue characteristics and mechanical evaluation of basalt fiber reinforced composite material concrete under freeze-thaw cycles. [PDF]
Sun H +6 more
europepmc +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Novel core-shell composite material based on polyacrylic acid salt and polyaniline for infrared camouflage applications. [PDF]
Ezzo HA, Almarjeh RAB, Atassi Y.
europepmc +1 more source
Jib crane lightweighting through composite material and prestressing technique
Luigi Solazzi, Nicola Danzi
openalex +1 more source
MATERIAL HETEROGENEITY OR STRESS CONCENTRATION: THE THERMOELASTIC RESPONSE FROM WOVEN COMPOSITE MATERIALS SUBJECTED TO CYCLIC FATIGUE [PDF]
R.K. Fruehmann +2 more
openalex +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Study on the Efficiency and Mechanism of a Novel Copper-Based Composite Material Activated by Supramolecular Self-Assembly for Degrading Reactive Red 3BS. [PDF]
Dai J, Wang X, Chen B, Chen L.
europepmc +1 more source
Dynamic optimization of a composite material robot arm using a flexible link and joint model
Marwah Ghazi Kareem +4 more
openalex +1 more source

