Results 201 to 210 of about 11,353,979 (422)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Effect on microstructure and mechanical properties of friction stir welded 5A06 aluminum alloy joints by deep cryogenic treatment

Materials Research Express
In order to improve the comprehensive mechanical properties of the welded joints of the 5A06 aluminum alloy, friction stir welded (FSW) joints were subjected to deep cryogenic treatment (DCT).
Jingjing Du, Mengke Qiao, Jun Wang, Liang Zhang, Wenzhuo Bian, Huixia Wang, Rui Sun, Yongdi Zhang, Shan Su   +8 more
doaj   +1 more source

7011) Study on the Fire Resistive Properties of Composite Panels Composed with Asbestos Cement Board and Lime-Type Insulating Materials-Report 3

, 1965
Makoto Mori
openalex   +2 more sources

Damping Measurements of a Controlled Composite Material [PDF]

, 1974
Eleanor Jones, R. L. Sierakowski, C. A. Ross   +2 more
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Evaluation of cryogenic insulation materials and composites for use in nuclear radiation environments. Materials test and propellant heating test. Quarterly progress report, 1 May--31 July 1968

, 1968
E. E. Kerlin, R.A. Elliott, R.D. Crabtree   +2 more
openalex   +2 more sources

Rim-spoke composite flywheels: Stress and vibration analysis [PDF]

Elementary relations are described to determine the material utilization efficiency of a thin wall rim composite flywheel over other configurations. An algorithm is generated for the automatic selection of the optimum composite material for a given thin ...
Chamis, C. C., Kiraly, L. J.
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Electrical Resistivity of Carbon Black-Kaolin Composite Sintered Materials. VII. Resistivity-Bulk Density Relations of C a rbon Black under Loose Contact

, 1966
Etsuro KATO, Masaru Hasegawa
openalex   +2 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source