Results 241 to 250 of about 11,353,979 (422)

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

The Effect of Textile Structure Reinforcement on Polymer Composite Material Mechanical Behavior. [PDF]

Polymers (Basel)
Risteska S, Srebrenkoska V, Zhezhova S, Srebrenkoska S, Risteski S, Jordeva S, Golomeova Longurova S.   +6 more
europepmc   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Study on the constitutive model and thermal deformation behavior of Incoloy825/P110 bimetallic composite material. [PDF]

Sci Rep
Liu H, Li Q, Gui H, Zhang C, Li S, Tuo L, Chen J, Zhang P, Shen C.   +8 more
europepmc   +1 more source

Composite materials for tokamak wall armor, limiters, and beam dump applications

, 1979
R.E. Riley, T.C. Wallace, J.M. Dickinson
openalex   +2 more sources

Materials: Fatigue in Composites [PDF]

, 1973

openalex   +1 more source

High-pressure synthesis of a polyethylene/zeolite nano-composite material

Nature Communications, 2013
M. Santoro, F. Gorelli, R. Bini, J. Haines, A. van der Lee   +4 more
semanticscholar   +1 more source

On the Composite Materials

Journal of Japan Institute of Light Metals, 1984
openaire   +2 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Obsidian: A Pioneering Natural Resource for Green, Fire-Resistant Composite Material Industries. [PDF]

ACS Omega
Hassan HS, Elshimy AS, Israde-Alcantara I, Abdel-Gawwad HA, Pfeiffer H.   +4 more
europepmc   +1 more source