Results 271 to 280 of about 10,977,169 (397)

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

STUDY ON INORGANIC COMPOSITE MATERIALS AS BUILDING MATERIALS

, 1977
Koichi Kishitani, Takayuki Hirai
openalex   +2 more sources

Preparation and Performance Research of Pb(II)-Imprinted Acrylonitrile-Co-Acrylic Acid Composite Material with Modified Sand Particles as Carrier. [PDF]

Polymers (Basel)
Sui Y, Gao S, Qi J, Abliz S, Chai L.
europepmc   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Pull-Out of Fibers from Composite Materials at High Rate of Loading

, 1979
Sadao AMIJIMA, Toru Fujii
openalex   +2 more sources

Evaluation of Mechanical Properties of Composite Material with a Thermoplastic Matrix Reinforced with Cellulose Acetate Microfibers. [PDF]

Polymers (Basel)
Rodríguez Sandoval P, Rubiano-Navarrete AF, Gómez-Pachón EY, Vera-Graziano R.   +3 more
europepmc   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

FEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei, Zhanbiao Liu, Jingjing Shi, Qian Jin, Wenqian Chen, Xuejun Chen, Liqin Li, Hui Chen   +7 more
wiley   +1 more source

STUDY ON INORGANIC COMPOSITE MATERIALS AS BUILDING MATERIALS : Part 3 Gypsum as The Matrix Phase in Composite Materials ; Mechanical Properties

, 1977
KOICHI KISHITANI, TAKAYUKI HIRAI
openalex   +2 more sources

Microwave Hybrid Sintering and Soldering of Cu-Cr-W Composite Material for Reactive Power Breakers. [PDF]

Materials (Basel)
Savu SV, Ghelsingher CD, Ștefan I, Sîrbu NA, Midan AA, Dumitru I, Savu ID, Nicolicescu C, David A.   +8 more
europepmc   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source