Results 331 to 340 of about 11,353,979 (422)

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

open access: yesFEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

From 2D to 3D gamma passing rate tolerance and action limits for patient‐specific quality assurance in volumetric‐modulated arc therapy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background Volumetric modulated arc therapy (VMAT) requires an accurate patient‐specific quality assurance (PSQA) program. In clinical practice, this is usually performed using the γ‐index and the two‐dimensional gamma passing rate (2D %GP). A three‐dimensional (3D) index incorporating the patient anatomy could be more useful for the 3D dose ...
Christos Zarros   +6 more
wiley   +1 more source

Commissioning of Halcyon enhanced leaf model in the Eclipse treatment planning system: Focus on simple slit fields and VMAT dose calculation

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose The dual‐layer multileaf collimator (MLC) in Halcyon adds complexities to the dose calculation process owing to the variability of dosimetric characteristics with leaf motion. Recently, an enhanced leaf model (ELM) was developed to refine the MLC model in the Eclipse treatment planning system. This study investigates the performance of
Ryohei Miyasaka   +6 more
wiley   +1 more source

Ultralight crystalline hybrid composite material for highly efficient sequestration of radioiodine. [PDF]

open access: yesNat Commun
Fajal S   +8 more
europepmc   +1 more source

A comparative analysis of deep learning architectures with data augmentation and multichannel input for locoregional breast cancer radiotherapy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Studies on deep learning dose prediction increasingly focus on 3D models with multiple input channels and data augmentation, which increases the training time and thus also the environmental burden and hampers the ease of re‐training. Here we compare 2D and 3D U‐Net models with clinical accepted plans to evaluate the appropriateness of
Rosalie Klarenberg   +2 more
wiley   +1 more source

A nanotrap infused ultrathin hybrid composite material for rapid and highly selective entrapment of 99TcO4. [PDF]

open access: yesChem Sci
Mandal W   +8 more
europepmc   +1 more source

Dose rate correction of a diode array for universal wedge field dosimetric verification

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To study the performance of MapCHECK 3 (MC3) in measuring universal wedge fields and propose a dose rate correction strategy to improve MC3 measurement accuracy. Materials and methods Universal wedge fields with different wedge angles and field sizes were measured at different depths using MC3.
Linyi Shen   +6 more
wiley   +1 more source

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