Results 41 to 50 of about 396,927 (251)
RGD peptide modified RBC membrane functionalized biomimetic nanoparticles for thrombolytic therapy
Journal of Materials Science: Materials in Medicine, 2023 In recent years, the fabrication of nano-drug delivery systems for targeted treatment of thrombus has become a research hotspot. In this study, we intend to construct a biomimetic nanomedicine for targeted thrombus treatment.
Zichen Xu +6 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Shifu‐Inspired Fungal Paper Yarns
Advanced ScienceFungal biorefinery is a popular method for producing advanced fabrics but is currently limited to leather alternatives and similar by the sheet‐based nature of most fungal materials.
Anne Zhao +3 more
doaj +1 more source
Life cycle assessment of lightweight natural fibre/PP-composite side skirts for electric trucks
Cleaner Environmental SystemsThe transportation sector faces increasing pressure to reduce greenhouse gas emissions, yet current solutions incorporating plastics and steel are heavy and energy-intensive, contributing significantly to climate impact.
Magdalena Juntikka +3 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Synthesis and Crystal Structure of the Bioinorganic Complex [Sb(Hedta)]·2H2O
Bioinorganic Chemistry and Applications, 2014 The antimony(III) complex [Sb(Hedta)]·2H2O was synthesized with ethylenediaminetetraacetic acid (H4edta) and antimonous oxide as main raw materials in aqueous solution. The composition and structure of the complex were characterized by elemental analysis,
Di Li, Guo-Qing Zhong
doaj +1 more source
Ion Release and Surface Characterization of Nanostructured Nitinol during Long-Term Testing
Nanomaterials, 2019 The corrosion resistance of nanostructured nitinol (NiTi) was investigated using long-term tests in solutions simulating physiological fluids at static conditions, reflecting the material structure and metal concentration in the solutions.
Elena O. Nasakina +4 more
doaj +1 more source