Results 131 to 140 of about 11,281,467 (414)

The PTTG1/VASP axis promotes oral squamous cell carcinoma metastasis by modulating focal adhesion and actin filaments

Molecular Oncology, EarlyView.
VASP was found to be overexpressed in metastatic oral squamous cell carcinoma (OSCC) tissues. Notably, PTTG1‐ and VASP‐deficient OSCC cells demonstrated suppressed metastatic properties by disrupting the interaction between the cytoskeleton and focal adhesion (FAs) in the filopodia region.
Suyeon Park, Sang Shin Lee, Shihyun Kim, Yeonjun Lee, Gyeonwon Park, Jung Oh Kim, Jongho Choi   +6 more
wiley   +1 more source

Designing high-performance composite joints close to parent materials of aluminum matrix composites [PDF]

arXiv, 2017
Composite joints with high-performance close to the parent materials of aluminum matrix composites were fabricated by a new joining technology assisted by ultrasonic vibration. We found both the microstructure and the mechanical performance were systematically dependent on the volume fraction and the distribution of reinforcement particles in the bond ...
arxiv  

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

Molecular Oncology, EarlyView.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang, Simone van de Weerd, Veerle Lammers, Sander van Hooff, Inge van den Berg, Saskia van den Bergh, Miriam Koopman, Jan N. IJzermans, Jeanine M. L. Roodhart, Jan Koster, Jan Paul Medema   +10 more
wiley   +1 more source

Theoretical design and experimental verification of high-entropy carbide ablative resistant coating

Advanced Powder Materials
Composition design of high-entropy carbides is a topic of great scientific interest for the hot-end parts in the aerospace field. A novel theoretical method through an inverse composition design route, i.e.
Lingxiang Guo, Shiwei Huang, Wei Li, Junshuai Lv, Jia Sun   +4 more
doaj  

Ablation resistance of C/C-HfC composites

Cailiao gongcheng
C/C-HfC composites with a density of 2.14 g/cm3 was successfully prepared using an inorganic hafnium solution as a precursor via chemical vapor infiltration (CVI) and precursor infiltration pyrolysis (PIP) methods, and its microstructure and composition ...
ZHENG Peng, LI Hong, YANG Min, YAO Yumin, REN Musu, SUN Jinliang   +5 more
doaj   +1 more source

On the effective permittivity of silver-insulator nanocomposites [PDF]

Journal of Nanophotonics, Vol. 1, 019501 (2007), 2006
The Bruggeman formalism provides an estimate of the effective permittivity of a composite material comprising two constituent materials, with each constituent material being composed of electrically small particles. When one of the constituent materials is silver and the other is an insulating material, the Bruggeman estimate of the effective ...
arxiv  

An overview on the application of FRP composites in piling system [PDF]

, 2010
Traditional pile materials such as steel, concrete and timber have limited service life when used in harsh marine environment. Problems coupled with these piles include deterioration of wood, corrosion of steel and degradation of reinforced concrete.
Aravinthan, T., Guades, E. J., Islam, M. M.   +2 more
core  

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

Composition, structure, and luminescent properties of SiOxNy(Si) composite layers containing Si nanocrystals [PDF]

arXiv, 2005
A relationship between the chemical composition, structure and luminescent properties of light-emitting SiOxNy(Si) composite layers with Si nanocrystals is demonstrated. Photoluminescence (PL) with a maximum of intensity at 500-600 nm is observed in a narrow region of chemical compositions with relatively small Si excess (about 10 at. %).
arxiv  

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

Molecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang, Anna Schritz, Nikolai Goncharenko, Guy Berchem   +3 more
wiley   +1 more source