Results 221 to 230 of about 1,533,936 (337)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Effect of Fiber Material on Tribological Performance of Filament-Winding Composite Materials in a Water-Lubricated Environment. [PDF]

Polymers (Basel)
Yu Y, Chen Z, Guo Z.
europepmc   +1 more source

Process simulation data for thermoforming of continuous fiber-reinforced composite materials

Johannes Mitsch, Luise Kärger
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Research on Alkali-Activated, Spinelized Kaolin Cementitious Composite Materials. [PDF]

Materials (Basel)
Feng Y, Gao C, Yuan F, Sun J, Li Q.
europepmc   +1 more source

Effects of cutting parameters on delamination during drilling of Polyphthalamide (PPA) Matrix Composite Material with 30% Glass Fiber Reinforcement

, 2015
Ferit Fıçıcı, Zekeriya Ayparcasi
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Research on Delamination Damage Factor of Hole-Making Process Optimization Based on Carbon Fiber Composite Materials. [PDF]

Polymers (Basel)
Liu L, Lai Y, Zhang Y, Huang L, Yang J, Jiang Y, Hu Z, Li Z, Wang B.   +8 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Radio-frequency sensor for non-destructive evaluation of composite materials. [PDF]

Sci Rep
Samolej K, Ślot M, Busiakiewicz A, Ślot MJ, Zasada I.   +4 more
europepmc   +1 more source