Results 141 to 150 of about 2,182,425 (310)
Liquid Molding Innovation: Membrane-Based RTM and VIP Processing
The University of Delaware Center for Composite Materials (UD-CCM) has discovered a Liquid Composite Molding (LCM) technique (patent pending) that significantly reduces resin waste while greatly improving robustness and part quality for Resin ...
Center for Composite Materials
core
A low cost and mechanically stabilized composite membrane (25 mu m) based on grafted porous polytetrafluoroethylene (grPTFE) substrate and partially fluorinated sulfonated poly(arylene ether ketone) (FSPAEK) polymer was fabricated and investigated for ...
Bi, Cheng +11 more
core +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Piezoelectric reverse osmosis (RO) membrane: fabrication and anti-fouling effect
In this study, a novel piezoelectric RO membrane with vibrating mechanism when exposed to an electric field was developed. The vibration due to the piezoelectric effect can disturb the concentration polarization layer on the membrane surface and minimize
Fu, Jia Shen +3 more
core +1 more source
Fabrication of a Fish-Bone-Inspired Inorganic-Organic Composite Membrane. [PDF]
Jiao Y +6 more
europepmc +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source

