Results 111 to 120 of about 693,874 (299)
Incremental Consistency Checking in Delta-oriented UML-Models for Automation Systems
, 2016 Automation systems exist in many variants and may evolve over time in order to deal with different environment contexts or to fulfill changing customer requirements.
Kowal, Matthias, Schaefer, Ina
core +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A finite element model capable of predicting resin pockets for arbitrary inclusions in composite laminates [PDF]
, 2012 This work presents the progress in the development of a finite element model capable of predicting resin pockets occurring in composite structures with embedded sensors.
Degrieck, Joris +3 more
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Nonlinear probabilistic finite element models of laminated composite shells [PDF]
A probabilistic finite element analysis procedure for laminated composite shells has been developed. A total Lagrangian finite element formulation, employing a degenerated 3-D laminated composite shell with the full Green-Lagrange strains and first-order
Engelstad, S. P., Reddy, J. N.
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Composite ALPs in Composite Higgs Models
Journal of High Energy PhysicsAbstract We study the effective Lagrangian for the Axion-Like Particle (ALP) arising in a class of composite Higgs models. We discuss the peculiarities of the coupling to the quark sector specific of these models, including flavor violating terms. We then confront the main bounds from rare B-meson decays.
openaire +2 more sources
, 2014 Learning compact and interpretable representations is a very natural task, which has not been solved satisfactorily even for simple binary datasets. In this paper, we review various ways of composing experts for binary data and argue that competitive forms of interaction are best suited to learn low-dimensional representations.
Goessling, Marc, Amit, Yali
openaire +2 more sources