Results 141 to 150 of about 693,874 (299)
Finite element modeling of frictionally restrained composite interfaces [PDF]
The use of special interface finite elements to model frictional restraint in composite interfaces is described. These elements simulate Coulomb friction at the interface, and are incorporated into a standard finite element analysis of a two-dimensional ...
Ahmed, Shamim, Ballarini, Roberto
core +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
PLoS ONEThe composite laminated rotationally stiffened shell is widely applied in aviation, aerospace, ship, machinery and other fields. To investigate the vibration characteristics of composite laminated rotationally stiffened shells with varying elastic ...
Dong Shi +4 more
doaj +1 more source
Mechanics-Based Modeling Approach for Rapid Prediction of Low Velocity Impact Damage in Composite Laminates [PDF]
A mechanics-based modeling approach is developed to rapidly predict damage in polymer matrix composites resulting from a low velocity impact event. The approach is incorporated into a computer code that provides an efficient means to assess the damage ...
Borkowski, Luke +2 more
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
High temperature composite analyzer (HITCAN) user's manual, version 1.0 [PDF]
This manual describes 'how-to-use' the computer code, HITCAN (HIgh Temperature Composite ANalyzer). HITCAN is a general purpose computer program for predicting nonlinear global structural and local stress-strain response of arbitrarily oriented ...
Gotsis, P. +3 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Impact of composite plates: Analysis of stresses and forces [PDF]
The foreign object damage resistance of composite fan blades was studied. Edge impact stresses in an anisotropic plate were first calculated incorporating a constrained layer damping model.
Fang-Landau, S. R. +2 more
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source