Single-Criterion Optimisation with Consideration of Uncertainties of the Composite Multi-Layer Slabs. [PDF]
Smela P, Miller B.
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A dataset of preclinical tooth preparation images. [PDF]
Fraiwan M, Al Fodeh R, Shamiyah D.
europepmc +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Effect of Y<sub>2</sub>O<sub>3</sub> Content on the Microstructure and Thermal Shock Resistance of Al<sub>2</sub>O<sub>3</sub>-Y<sub>2</sub>O<sub>3</sub> Composite Coatings. [PDF]
Hu Z +6 more
europepmc +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Effect of Different Specimen Preparation Methods on Dentin Shear Bond Strength: Polyethylene Tubes vs Jig System. [PDF]
Balaban Karakaş S +3 more
europepmc +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Using factor models to construct composite indicators from BCS data - a comparison with European Commission confidence indicators [PDF]
This paper compares different approaches to constructing composite business cycle indicators based on series from the Joint Harmonised EU Programme of Business and Consumer Surveys (BCS).
Julien Genet, Christian Gayer
core
Effect of thermal aging on the radiopacity of universal composite resins at two thickness levels. [PDF]
Ozdemir SB, Ozdemir B.
europepmc +1 more source

