Results 281 to 290 of about 2,099,767 (349)

Mechanical mechanism of soil consolidation by plant roots in loess area of northern Shaanxi. [PDF]

Sci Rep
Xu R, He Y, Cheng H, Deng J, Wei H, Wang G, Li X, Yang W.   +7 more
europepmc   +1 more source

FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production

FEBS Open Bio, EarlyView.
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley   +1 more source

Application of the anti-IgLON5 disease composite score to assess severity, clinical course, and mortality in a French cohort. [PDF]

J Neurol
Farina A, Villagrán-García M, Abichou-Klich A, Benaiteau M, Bernard E, Campetella L, Cluse F, Desestret V, Dumez P, Fabien N, Goncalves D, Muñiz-Castrillo S, Picard G, Pinto AL, Rogemond V, Vogrig A, Joubert B, Honnorat J.   +17 more
europepmc   +1 more source

The Composite Number Needed to Treat for Semaglutide in Populations with Overweight or Obesity and Established Cardiovascular Disease Without Diabetes

Christopher Lübker, Jigish Bhavsar, Ruben Vale, Scott S. Emerson, Emil Nørtoft, Jorge Plutzky, Geraint Roberts, Jens M. Tarp, A. Michael Lincoff   +8 more
openalex   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Numerical and experimental study of the effect of an edge crack on the vibration characteristics of UD and quasi-isotropic GFRP cantilever composite beam. [PDF]

Sci Rep
Achenef Eshete M, Adimass SA, Paramasivam V.   +2 more
europepmc   +1 more source

On composite types of tunnel number two knots

, 2014
Kanji Morimoto
openalex   +2 more sources

A potential tumor suppressor role of PLK2 in glioblastoma

FEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia, Peirui Wang, Hua Xiao, Qishan Ran, Yan Li, Shengtao Yao   +5 more
wiley   +1 more source

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

Restorative management of permanent teeth affected by molar incisor hypomineralization: a survey of dentists in Saudi Arabia. [PDF]

BMC Oral Health
Bagher SM, Alahdal RE, Alzanbaki SA, Abudawood SN, Felemban OM.   +4 more
europepmc   +1 more source