Results 71 to 80 of about 2,099,767 (349)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Direct test of composite fermion model in quantum Hall systems
We show that neutron scattering and Raman scattering experiments can unambiguously determine a composite fermion parameter, viz., the effective number of Landau Levels filled by the composite fermions.
A. H. MacDonald+30 more
core +1 more source
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Four primality testing algorithms [PDF]
In this expository paper we describe four primality tests. The first test is very efficient, but is only capable of proving that a given number is either composite or 'very probably' prime.
Schoof, Rene
core +2 more sources
Effective mass of the composite fermion in the fractional quantum Hall system, which is of purely interaction originated, is shown, from a numerical study, to exhibit a curious nonmonotonic behavior with a staircase correlated with the number (=2,4 ...
A. Lopez+20 more
core +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Effect of Number of Layer in Composite Sheet
Composite material is commonly used in most industries: it became a basic substance for generating electric energy in many industries, aircraft , automobile and air turbine Composite material is a big family and it is classified into many kinds like ...
B. A. Sadkhan
doaj
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard+7 more
wiley +1 more source
Compound composite odontoma with unusual number of denticles – A rare entity
Compound odontoma is stated to be a hamartomatous lesion rather than a true odontogenic tumour. It has an unknown etiology and often suspected when there are retained deciduous teeth in children.
Urvashi Sharma+4 more
doaj
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr+4 more
wiley +1 more source