Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
wiley +1 more source
Fatigue failure of prefabricated crack HTPB(hydroxyl-terminated polybutadiene) propellant under strain control. [PDF]
Li G, Gao B, Hu H, Cui R, Feng J, He J.
europepmc +1 more source
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei +17 more
wiley +1 more source
Influence of Process Aids on Solid-Liquid Interfacial Properties of Three-Component Hydroxyl-Terminated Polybutadiene Propellants. [PDF]
Zhang X +7 more
europepmc +1 more source
Integrating Spatial Proteogenomics in Cancer Research
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang +13 more
wiley +1 more source
Research on Curing Reaction Kinetics and Curing Process of Nitrate Ester Plasticized Polyether (NEPE) Propellants. [PDF]
Wu Y, Guo Z, Yu H, Fu X.
europepmc +1 more source
A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang +7 more
wiley +1 more source
UV-Assisted Material Extrusion Additive Manufacturing of Double-Base Propellant. [PDF]
Li M +5 more
europepmc +1 more source
A Fully Self‐Powered Digital Wearable System for the Auxiliary Treatment of Plantar Fasciitis
This study reports a system‐level fully self‐powered digital wearable system (FS‐DWS) for the auxiliary treatment of plantar fasciitis. By integrating arch support, energy harvesting, wearable sensing, and machine learning‐driven closed‐loop visualized feedback, the system enables effective plantar pressure reduction and self‐powered, real‐time plantar
Jiacheng Hou +10 more
wiley +1 more source
Effect of Octa(perfluorodecyl)-Type Polyhedral Oligomeric Silsesquioxanes on Combustion Characteristics of the Mixed Nitrate Ester Gun Propellant. [PDF]
Du X, Liu X, Zhao L, Wang X, Li G.
europepmc +1 more source

