Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
In vitro attrition wear resistance of four types of paste-like bulk-fill composite resins
Background Recently, the application of bulk-fill composite resins has increased significantly. Attrition wear and the consequently increased surface roughness of composite resins are among the causes of restoration failure in the posterior teeth.
Faeze Asadian +5 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Background: Loss of tooth structure is a consideration in the performance of restorative treatment involving nanofilled composite resins. Material polymerization factors and water absorption can affect the hardness of composite resins.
Titis Mustikaningsih Handayani +4 more
doaj +1 more source
Relative biocompatibility of micro-hybrid and nano-hybrid light-activated composite resins [PDF]
Background. In vitro studies have revealed a direct association between resin content and cytotoxicity of composite re-sins; however, implantation studies in this regard are sparse.
Abiodun Olabisi Arigbede +2 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Development of novel flax bio-matrix composites for non-structural and structural vehicle applications [PDF]
The use of natural fibres (e.g. flax, hemp etc.) instead of synthetic fibres (carbon and glass etc.) as composite reinforcements not only benefits the environment, but also provides economical lightweight products for transports.
Zhu, Jinchun
core +5 more sources
Erosion of Composite Resins [PDF]
The surface degradation of composite resins caused by accelerated aging was studied. Accelerated aging for 900 hours caused erosion of the resin matrices and exposure of filler particles. Differences in surface profiles after aging suggest that the materials eroded at different rates. Accelerated aging may model erosive wear of composites.
Powers, John M., Fan, P. L.
openaire +3 more sources
Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source

