Results 151 to 160 of about 2,317,233 (285)

EXPERIMENTAL STUDY ON SHEAR BEHAVIOR OF NEW COMPOSITE SHEAR WALL SYSTEM

open access: yesJournal of Structural and Construction Engineering (Transactions of AIJ), 2004
Toko HITAKA, Kenji SAKINO
openaire   +2 more sources

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

open access: yesAdvanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao   +5 more
wiley   +1 more source

Cracking and tension field action in composite beams [PDF]

open access: yes
Two aspects of the behaviour of uncased composite 'T' beams of steel and concrete are considered. Flexural cracking in the reinforced concrete slab was studied by subjecting seven 350-mm deep composite beams to hogging bending moment.
Allison, Robert William
core  

Sustainable Fabrication of Tailored Bone Substitutes: From High‐Throughput Scaffold Manufacturing, Scaled‐Up HMSC Expansion to Dynamic Cultivation in a Perfusion Bioreactor

open access: yesAdvanced Science, EarlyView.
ABSTRACT The demand for off‐the‐shelf biocompatible bone substitutes has driven the development of numerous independent in vitro technologies to generate products resembling physiological tissues. Due to technical challenges and overly simplified cultivation approaches/niches, the end‐products are often uniformly shaped and inferior to native bone ...
Franziska Braun   +10 more
wiley   +1 more source

Celastrol‐Loaded Conductive Hydrogel Mitigates Myocardial Ischemia‐Reperfusion Injury and Restores Electrophysiological Function

open access: yesAdvanced Science, EarlyView.
Schematic illustration of the Pluronic F127 diacrylate/gelatin methacryloyl/poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate)/celastrol hydrogel (FGPC) for localized myocardial ischemia–reperfusion injury treatment. FGPC combines sustained celastrol delivery with PEDOT:PSS‐mediated conductive support to attenuate acute oxidative/inflammatory ...
Shixin Wang   +10 more
wiley   +1 more source

Shear strength and moment-shear interaction of steel-concrete composite beams:Experiments, numerical analyses, and design models

open access: yes, 2012
Current structural codes do not address the shear strength and the moment-shear interaction in composite beams explicitly. The shear is commonly assumed to be resisted by the steel beam alone neglecting the contributions of the slab and the composite ...
Uy, Brian (R9735)   +3 more
core  

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