Results 151 to 160 of about 10,802 (309)

Apollo Lightcraft Project [PDF]

The ultimate goal for this NASA/USRA-sponsored Apollo Lightcraft Project is to develop a revolutionary manned launch vehicle technology which can potentially reduce payload transport costs by a factor of 1000 below the Space Shuttle Orbiter.
Atonison, Mark A., Chen, Sammy G., Decusatis, Casimer, Kusche, Karl P., Minucci, Marco A., Moder, Jeffrey P., Morales, Ciro, Myrabo, Leik N., Nelson, Caroline V., Richard, Jacques C.   +9 more
core   +1 more source

Halofuginone is a Molecular Glue Degrader of Integrin β4

Advanced Science, EarlyView.
Integrin β4 overexpression is linked to aggressive tumors and poor prognosis, but targeted therapies are lacking. We identified halofuginone (HF) as a molecular glue degrader that promotes integrin β4 degradation via the CRL4BWDR18 E3 ligase. HF suppresses tumor progression in vitro and in vivo, offering a new strategy for targeting oncogenic ...
Wei Gong, Di Yang, Junrui Tian, Yufei Chai, Tiantian Yu, Qingnan Wu, Yan Wang, Weimin Zhang, Qimin Zhan   +8 more
wiley   +1 more source

Development of a computerized analysis for solid propellant combustion instability with turbulence [PDF]

A multi-dimensional numerical model has been developed for the unsteady state oscillatory combustion of solid propellants subject to acoustic pressure disturbances.
Chung, T. J., Park, O. Y.
core   +1 more source

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

Advanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong, James Trevarthen, Igor Dolbnya, Wadwan Singhapong, Nicholas Pilato, Richard Butler, Jiraphant Srisuriyachot, Alexander J. G. Lunt   +7 more
wiley   +1 more source

Novel Approach for the Fabrication of Composite Rocket Propellant: Increased Homogeneity and Its Influence on SRP Behaviour. [PDF]

Materials (Basel)
Janowska K, Procek M, Warski T, Polis M, Stolarczyk A, Hawelek L.   +5 more
europepmc   +1 more source

Space Transportation Materials and Structures Technology Workshop [PDF]

The Space Transportation Materials and Structures Technology Workshop was held on September 23-26, 1991, in Newport News, Virginia. The workshop, sponsored by the NASA Office of Space Flight and the NASA Office of Aeronautics and Space Technology, was ...
Cazier, Frank W., Jr., Gardner, James E.
core   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Novel glycidyl azide polymers containing aromatic diol units: synthesis and characterization for their application as energetic composite propellant binders. [PDF]

RSC Adv
Le-Nhat-Thuy G, Tuyet Anh DT, Hung VQ, Quynh Giang NT, Anh NT, Phuong HT, Thanh NH, Mai DT, Van Tuyen N.   +8 more
europepmc   +1 more source

Design Optimization of Gas Generator Hybrid Propulsion Boosters [PDF]

A methodology used in support of a study for NASA/MSFC to optimize the design of gas generator hybrid propulsion booster for uprating the National Space Transportation System (NSTS) is presented.
Fink, Larry, Phillips, Dwight, Weldon, Vincent   +2 more
core   +2 more sources

A Bioinspired Three‐Dimensional High‐Curvature Nano‐Interface Integrated Microfluidic Chip for Small Extracellular Vesicles Enrichment and Machine Learning‐Assisted Prostate Cancer Precision Diagnosis

Advanced Science, EarlyView.
A biotin‐modified artificial insertion peptide functionalized three‐dimensional high‐curvature‐TiO2 nano‐interface was engineered in a microfluidic chip to improve the isolation efficiency of small extracellular vesicles (sEVs). This chip balanced affinity, releasability, and extendibility, enabling high‐throughput recovery of sEVs for downstream ...
Le Wang, Yizhong Liang, Manan Sulaiman, Jiaqi Du, Ming Jiang, Zhihua Wang, Xu Yu, Li Xu   +7 more
wiley   +1 more source