Results 111 to 120 of about 15,021,574 (352)

Advanced technology composite aircraft structures [PDF]

open access: yes
Work performed during the 25th month on NAS1-18889, Advanced Technology Composite Aircraft Structures, is summarized. The main objective of this program is to develop an integrated technology and demonstrate a confidence level that permits the cost- and ...
Ilcewicz, Larry B., Walker, Thomas H.
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Composite structural materials [PDF]

open access: yes
The use of filamentary composite materials in the design and construction of primary aircraft structures is considered with emphasis on efforts to develop advanced technology in the areas of physical properties, structural concepts and analysis ...
Ansell, G. S.   +2 more
core   +4 more sources

Integrated analysis and design of thick composite structures for optimal passive damping characteristics [PDF]

open access: yes
The development of novel composite mechanics for the analysis of damping in composite laminates and structures and the more significant results of this effort are summarized.
Saravanos, D. A.
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Atmospheric Structure and Composition

open access: yes, 2009
Titan's atmosphere is predominantly N2 with CH4 the next most abundant molecule. It has a mole fraction of 0.05 just above the surface decreasing to 0.014 in the stratosphere. Above the homopause (~800–850 km), it increases to 0.12 at the exobase. The third abundant molecule is H2 with a tropospheric mole fraction of 0.001 increasing to 0.004 at ~1000 ...
Strobel, Darell   +9 more
openaire   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Eighth DOD/NASA/FAA Conference on Fibrous Composites in Structural Design, Part 2 [PDF]

open access: yes
Papers presented at the conference are compiled. The conference provided a forum for the scientific community to exchange composite structures design information and an opportunity to observe recent progress in composite structures design and technology.
Bohon, Herman L.   +2 more
core   +1 more source

Hybrid composite laminate structures [PDF]

open access: yes, 1977
An invention which relates to laminate structures and specifically to essentially anisotropic fiber composite laminates is described. Metal foils are selectively disposed within the laminate to produce increased resistance to high velocity impact ...
Chamis, C. C., Lark, R. F.
core   +1 more source

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