Results 181 to 190 of about 1,068,348 (298)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Effects of SiC Particle Size on SiC_p/Al Composite During Vacuum Hot Pressing. [PDF]

Materials (Basel)
Feng R, Wu H, Liu H, Yang Y, Pei B, Han J, Liu Z, Wu X, Huang Z.   +8 more
europepmc   +1 more source

Bolted double-lap composite joints under mechanical and thermal loading [PDF]

, 2001
Vladimir Kradinov, A. O. Barut, Erdogan Madenci, Damodar Ambur   +3 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Impact of partial cement dust replacement in unsaturated polyester: assessing material performance and waste valorization for sustainable management. [PDF]

Sci Rep
Syala E, Sadik WA, El-Demerdash AM, Mekhamer W, El-Rafey ME.   +4 more
europepmc   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Biowastes as Reinforcements for Sustainable PLA-Biobased Composites Designed for 3D Printing Applications: Structure-Rheology-Process-Properties Relationships. [PDF]

Polymers (Basel)
Ait Balla M, Maazouz A, Lamnawar K, Arrakhiz FE.   +3 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Enhanced mechanical and thermal properties of polyester/glass/sheep wool fiber hybrid composites by successful replacement glass with wool. [PDF]

Sci Rep
Sadroddini M.
europepmc   +1 more source

Oxidation-responsive, settable bone substitute composites for regenerating critically-sized bone defects

Rogério Lacerda dos Santos, Asrar Ahmed, Brooke E. Hunn, Adrian Addison, Daiane Maria da Silva Marques, K Bruce, John R. Martin   +6 more
openalex   +2 more sources