Results 211 to 220 of about 3,382,988 (388)

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Addressing data scarcity in deep learning: Leveraging real and artificial datasets to predict compaction of composites

open access: yesMaterials & Design
This study focuses on predicting the compaction behaviour of composite materials under processing conditions using Long Short-Term Memory (LSTM) neural networks.
Anatoly Koptelov   +4 more
doaj  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Study of composites as substrate materials in large space telescopes [PDF]

open access: yes
Nonmetallic composites such as the graphite/epoxy system were investigated as possible substrates for the primary mirror of the large space telescope. The possible use of fiber reinforced metal matrix composites was reviewed in the literature.
Sharma, A. V.
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Zirconia toughened SiC whisker reinforced alumina composites small business innovation research [PDF]

open access: yes
The objective of this phase 1 project was to develop a ceramic composite with superior fracture toughness and high strength, based on combining two toughness inducing materials: zirconia for transformation toughening and SiC whiskers for reinforcement ...
Lee, C. T.   +3 more
core   +1 more source

Fiber-reinforced geopolymer composites: A review

open access: yesCement & Concrete Composites, 2020
Navid Ranjbar, Mingzhong Zhang
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy