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Novel Bioconjugate Materials: Synthesis, Characterization and Medical Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses the bioconjugation of novel materials grouped under “biological”, “hybrid” and “synthetic” categories. Medical applications ranging from cancer therapy and diagnostics to optogenetics and tissue engineering are explored, and conjugation trends are highlighted as a general guide. The review concludes with a comparison of techniques
Ellie Martin   +6 more
wiley   +1 more source

Conditioned Media from Mechanically Stimulated Macrophages Upregulate Osteogenic Genes in Human Mesenchymal Stromal Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex   +4 more
wiley   +1 more source

Large language model-based description is all you need: Zero-shot medical concept embeddings using Transformer encoders

open access: yes
Zaghir J   +8 more
europepmc   +1 more source

Xeno‐Free Biocompatible Peptide‐Based Bioinks Reinforced with Cellulose Nanofibers for 3D Printing

open access: yesAdvanced Healthcare Materials, EarlyView.
A xeno‐free bioink combining self‐assembled peptides and cellulose nanofibers is developed for 3D printing. The bioink forms a non‐cross‐linked 3D scaffold, mimicking the extracellular matrix and supporting over 95% cell viability. This approach offers enhanced biocompatibility and mechanical stability, advancing 3D printing for personalized medicine ...
Francesca Netti   +5 more
wiley   +1 more source

Functionalized Reduced Graphene Oxide‐Based Nanocomposite Hydrogels for Enhanced Osteogenesis in Bone Tissue Engineering

open access: yesAdvanced Healthcare Materials, EarlyView.
Charge‐opposed reduced graphene oxide fillers are co‐integrated into biopolymeric nanocomposite scaffolds, synergistically enhance osteogenesis. Multiscale characterization reveals how surface chemistry and porosity dictate ectopic mineral architecture.
George Mihail Vlăsceanu   +8 more
wiley   +1 more source

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