Results 91 to 100 of about 24,840,318 (307)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

A phylogenetic transform enhances analysis of compositional microbiota data

eLife, 2017
Surveys of microbial communities (microbiota), typically measured as relative abundance of species, have illustrated the importance of these communities in human health and disease.
Justin D Silverman, Alex D Washburne, Sayan Mukherjee, Lawrence A David   +3 more
doaj   +1 more source

Distributional equivalence and subcompositional coherence in the analysis of contingency tables, ratio-scale measurements and compositional data [PDF]

We consider two fundamental properties in the analysis of two-way tables of positive data: the principle of distributional equivalence, one of the cornerstones of correspondence analysis of contingency tables, and the principle of subcompositional ...
Paul Lewi, Michael Greenacre
core  

Exploration of geochemical data with compositional canonical biplots [PDF]

, 2018
The study of the relationships between two compositions is of paramount importance in geochemical data analysis. This paper develops a compositional version of canonical correlation analysis, called CoDA-CCO, for this purpose. We consider two approaches,
Graffelman, Jan, Buccianti, A., Pawlowsky Glahn, Vera, Egozcue Rubí, Juan José, Buccianti A, PawlowskyGlahn V, Egozcue J, Buccianti, Antonella, Graffelman J   +8 more
core   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Commentary: How to Count Our Microbes? The Effect of Different Quantitative Microbiome Profiling Approaches

Frontiers in Cellular and Infection Microbiology, 2021
Ching Jian, Anne Salonen, Katri Korpela
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Methods to Detect Outliers in Compositional Data with Structural Zeros

, 2013
Outlier Detection, Zeros, Compositional ...
Monti, Gianna, Filzmoser, Peter, Templ, Matthias, Hron, Karel   +3 more
core   +2 more sources

Addressing Dependent Data in Constrained Optimization Problems: A WOA-based Algorithm [PDF]

International Journal of Industrial Electronics, Control and Optimization
Optimization algorithms are widely used in various fields to find the best solution to a problem by minimizing or maximizing an objective function, subject to certain constraints.
Asieh Ghanbarpour, Soheil Zaremotlagh, Fahimeh Dabaghi-Zarandi   +2 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source