Results 111 to 120 of about 952,046 (252)
Review of the protective effects of compound 21 and valsartan in iso-induced heart failure in rats
, 2017 Amaç: İsoproterenol ile in vivo kalp yetmezliği geliştirilmiş ratlarda ilk non peptit yapıda ve spesifik AT2 reseptör agonisti olan compound 21' in kardiyak hasardan koruyucu etkilerini araştırmak ve AT1 reseptör antagonisti olan valsartan ile ...
Ulutaş Kurnaz, Zeynep
core
Terrestrial water storage in Australia under stress from compound climate extremes
A large proportion of human population could be exposed to future risks from compound climate extremes, which are threatening food and water security.
Adeyeri, Oluwafemi E +3 more
core +1 more source
Scientific Reports, 2017 LH-21 is a triazol derivative that has been described as a low-permeant neutral CB1 antagonist, though its pharmacology is still unclear. It has been associated with anti-obesity actions in obese rats. However, its role in preventing type 2 diabetes (T2D)
Silvana Y. Romero-Zerbo +10 more
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
X-ray scattering studies of compound semiconductors [PDF]
, 1997 In this thesis, techniques of high resolution x-ray diffraction, topography and grazing incidence reflectivity have been employed in order to gain information on compound semiconductors. A recent growth technique. Vertical Gradient Freeze (VGF), has been
Moore, C.D., Moore, Caroline Dale
core
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018 A series of 2-amino-5-nitrothiazole derived semicarbazones were designed, synthesised and investigated for MAO and ChE inhibition properties. Most of the compounds showed preferential inhibition towards MAO-B. Compound 4, (1-(1-(4-Bromophenyl)ethylidene)-
Rati K. P. Tripathi +4 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
, 2019 For Laptop OrchestraComposed in 2015Composed for Gail Priest and ERK (Electronic Resonance Korp).You need the Decibel ScorePlayer and the score file (provided here) to peform this work.PROGRAM NOTE10.4 Forcible transfer of children to Bravo Compound at ...
Cat Hope (4542307)
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source