Results 81 to 90 of about 952,046 (252)
Effect of compound 21 administration on blood glucose, insulin, and adipocytokines in KK-Ay mice.
, 2013 Concentrations of blood glucose (A) and serum insulin (B) in KK-Ay mice treated with compound 21 (C21). KK-Ay mice were treated as described in ‘Methods’. Some KK-Ay mice treated with C21 were concurrently administered GW9662, a PPARγ antagonist.
Tomas Unger (298899) +11 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
MANAGEMENT OF BURN WOUNDS BY COMPOUND AYURVEDIC PREPERATION CHANDANADI YAMAKAM
, 2010 No injury sustained by the man is so frightful with the complications, as the burn wound. Loss of skin with all its protective and homeostatic functions exposes the body to variety of stresses which are not seen in any other type of injury.
P, Kumar T +3 more
core +1 more source
Synthesis and Characterization of New Thioxanthone Derivatives
مجلة بغداد للعلوم, 2013 This work comprises the synthesis of new thioxanthone derivatives containing C-substituted thioxanthone. To obtain these derivatives, the o-mercapto benzoic acid was chosen as the starting material, which was reacted with dry ...
Baghdad Science Journal
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
2,4,5-Triphenyl-1,3,2-dioxaphospholan-2-one
, 2011 Funding: University of St Andrews and the EPSRC, UK.The dioxaphospholane ring in the title compound, C20H17O3P, adopts an envelope conformation about one of the ring carbons.
Woollins, J. Derek +7 more
core +1 more source
Fluorescence/luminescence-based markers for the assessment of Schistosoma mansoni schistosomula drug assays [PDF]
, 2015 Schistosomiasis is responsible for a tremendous public health burden, yet only a single drug, praziquantel, is available. New antischistosomal treatments should therefore be developed. The accuracy, speed and objectivity of in vitro drug screening depend
Gordana Panic +7 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Effect of compound 21 on body weight in KK-Ay mice.
, 2013 Animals were fed normal standard diet for 2 weeks. Values are mean±SEM of 15 to 20 mice for each group.
Tomas Unger (298899) +11 more
core +1 more source