Results 201 to 210 of about 348,445 (260)

Combined effects of apparent low temperature and PM_2.5 pollution on circulatory emergency ambulance calls: a time-series analysis in Shijiazhuang, China. [PDF]

Front Public Health
Chen S, Li M, Ding Y, Xu N, Guan M, Chen F, Tong J.   +6 more
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Real-world and computational identification of herbal candidates associated with adverse event patterns in glucagon-like peptide-1 therapy for obesity. [PDF]

Sci Rep
Park J, Shin S, Kim Y, Seo J, Kim B, Lee K.   +5 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Bilateral detection, prediction, and lateralization of seizures using white matter. [PDF]

Epilepsia Open
Pakalapati N, Chiang CC, Lokam S, Durand DM.   +3 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

PKD2L1 channels segregated to the apical compartment are the dual-mode pH sensor in cerebrospinal fluid-contacting neurons. [PDF]

Elife
Vitar M, Prieto D, Malas S, Russo RE, Trigo FF.   +4 more
europepmc   +1 more source

Form informs function: innervation patterns of projection neurons correspond to response profiles of mushroom body output neurons during olfactory-visual integration. [PDF]

Front Physiol
Aliyam Veetil Zyndheen AA, Nicolaidou AR, Groh C, Dürr V, Rössler W, Strube-Bloss M.   +5 more
europepmc   +1 more source

Association between compound PM_2.5-cold events and population-specific mortality: a time-trend ecologic study of damage amplification in Zigong, China. [PDF]

Arch Public Health
Xia Y, Huang W, Zhang Z, Li Y, Chen Y, Ren H, Meng F, Qin X, Jiang P, Jin X, Zhou B, Chen X.   +11 more
europepmc   +1 more source

Compound climate extreme events and associated health impacts: a scoping review. [PDF]

BMC Med
Mathews S, Walker C, Gao K, Madrigano J.
europepmc   +1 more source